1. MetaboLights
  2. Compound page
MOL SMILES InChIKey
Export Upload Reference Spectra Help

A natural product found in Ficus mucuso.

Identification

Molecular Formula
C20H20O6
Mass
356.36920
Monoisotopic Mass
356.12599
Charge
0
InChI
InChI=1S/C20H18O5.H2O/c1-11(2)3-4-13-7-12(5-6-16(13)22)15-10-25-18-9-14(21)8-17(23)19(18)20(15)24;/h3,5-10,21-23H,4H2,1-2H3;1H2
InChIKey
WFALQMZTKNBBMO-UHFFFAOYSA-N
SMILES
[H]O[H].CC(C)=CCc1cc(ccc1O)-c1coc2cc(O)cc(O)c2c1=O
Synonyms

5,7-dihydroxy-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]chromen-4-one hydrate

Species

ficus mucuso

NCBI:txid309328 21619045

Europe PubMed Central results

Isoflavone dimers and other bioactive constituents from the figs of Ficus mucuso.

Author: Bankeu JJ, Khayala R, Lenta BN, Noungoué DT, Ngouela SA, Mustafa SA, Asaad K, Choudhary MI, Prigge ST, Hasanov R, Nkengfack AE, Tsamo E, Ali MS.

Abstract: Phytochemical investigation of the figs of Ficus mucuso led to the isolation of three new isoflavone dimer derivatives, mucusisoflavones A-C (1-3), together with 16 known compounds. Some of the isolates were tested in vitro for their inhibitory properties toward β-glucuronidase and Plasmodium falciparum enoyl-ACP reductase (PfENR) enzymes. Compound 1 (IC₅₀) 0.68 μM) showed inhibitory activity on β-glucuronidase enzyme, while 3 (IC₅₀) 7.69 μM) exhibited a weak inhibitory activity against P. falciparum enoyl-ACP reductase (PfENR).