PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=747-J8-MJ4)

Interfaces in PDB 2cm8 crystal.
Space symmetry group: P 31 2 1. Resolution: 2.10 Å

STRUCTURAL BASIS FOR INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B BY ISOTHIAZOLIDINONE HETEROCYCLIC PHOSPHONATE MIMETICS

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`80`	`23`	`13362`	`x`	A	-y+1,x-y,z+1/3	`2_655`	`58`	`16`	`13362`	`615.9`	`-3.7`	`0.249`	`6`	`3`	`0`	`0.000`
`2`		A	`30`	`10`	`13362`	`x`	A	-x+1,-x+y,-z+1/3	`6_655`	`35`	`12`	`13362`	`325.7`	`-2.7`	`0.279`	`3`	`3`	`0`	`0.000`
`3`		[F16]A:1299	`15`	`1`	`375`	`f`	A	x,y,z	`1_555`	`37`	`13`	`13362`	`242.1`	`3.0`	`0.657`	`8`	`0`	`0`	`0.014`
`4`		[MG]A:1300	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`7`	`3`	`13362`	`29.7`	`-3.1`	`0.000`	`0`	`0`	`0`	`0.086`
`5`		A	`3`	`1`	`13362`	`◊`	[MG]A:1300	-x+1,-x+y,-z+1/3	`6_655`	`1`	`1`	`98`	`23.4`	`-2.2`	`0.000`	`0`	`0`	`0`	`0.000`
`6`		A	`2`	`1`	`13362`	`◊`	[F16]A:1299	-y+1,x-y,z+1/3	`2_655`	`2`	`1`	`375`	`19.5`	`-0.3`	`0.399`	`0`	`0`	`0`	`0.000`
`7`		A	`4`	`1`	`13362`	`◊`	A	-x+2,-x+y+1,-z+1/3	`6_765`	`4`	`1`	`13362`	`12.6`	`-0.4`	`0.437`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe