PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=827-GK-A66)

Interfaces in PDB 2viq crystal.
Space symmetry group: P 21 21 21. Resolution: 2.00 Å

FRAGMENT-BASED DISCOVERY OF MEXILETINE DERIVATIVES AS ORALLY BIOAVAILABLE INHIBITORS OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`58`	`18`	`11453`	`x`	A	-x+1,y-1/2,-z+1/2	`3_645`	`44`	`15`	`11453`	`490.9`	`-3.4`	`0.287`	`4`	`4`	`0`	`0.000`
`2`		[D55]A:1246	`27`	`1`	`661`	`f`	A	x,y,z	`1_555`	`61`	`27`	`11453`	`373.3`	`3.8`	`0.169`	`4`	`0`	`0`	`0.000`
`3`		A	`34`	`14`	`11453`	`x`	A	x-1/2,-y-1/2,-z+1	`4_446`	`33`	`10`	`11453`	`277.8`	`0.7`	`0.601`	`2`	`0`	`0`	`0.000`
`4`		A	`27`	`7`	`11453`	`x`	A	x-1,y,z	`1_455`	`33`	`10`	`11453`	`269.0`	`-0.2`	`0.555`	`2`	`0`	`0`	`0.000`
`5`		A	`32`	`9`	`11453`	`x`	A	x-1/2,-y+1/2,-z+1	`4_456`	`30`	`10`	`11453`	`255.8`	`0.6`	`0.645`	`3`	`0`	`0`	`0.000`
`6`		A	`28`	`10`	`11453`	`x`	A	-x+1/2,-y,z-1/2	`2_554`	`19`	`6`	`11453`	`246.9`	`0.9`	`0.675`	`3`	`1`	`0`	`0.000`
`7`		[ACT]A:1245	`4`	`1`	`182`	`f`	A	x,y,z	`1_555`	`14`	`8`	`11453`	`83.1`	`-0.3`	`0.626`	`4`	`0`	`0`	`0.000`
`8`		[D55]A:1246	`11`	`1`	`661`	`f`	[ACT]A:1245	x,y,z	`1_555`	`4`	`1`	`182`	`61.3`	`0.5`	`0.237`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe