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PISA Interface List.

Session Map (id=814-G8-4F9)

Interfaces in PDB 2y6c crystal.
Space symmetry group: I 4. Resolution: 1.70 Å

THE DISCOVERY OF MMP7 INHIBITORS EXPLOITING A NOVEL SELECTIVITY TRIGGER

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`66`	`27`	`8160`	`x`	A	-y,x,z	`3_555`	`59`	`17`	`8160`	`566.4`	`-4.3`	`0.424`	`8`	`1`	`0`	`0.185`
`2`		A	`60`	`18`	`8160`	`◊`	A	-x,-y-1,z	`2_545`	`60`	`18`	`8160`	`517.1`	`-1.7`	`0.625`	`9`	`0`	`0`	`0.000`
`3`		A	`30`	`9`	`8160`	`x`	A	-y-1/2,x-1/2,z-1/2	`7_444`	`27`	`9`	`8160`	`232.9`	`-2.9`	`0.323`	`2`	`0`	`0`	`0.000`
`4`		A	`21`	`6`	`8160`	`x`	A	-x-1/2,-y-1/2,z-1/2	`6_444`	`20`	`6`	`8160`	`205.8`	`-2.2`	`0.339`	`2`	`0`	`0`	`0.000`
`5`		[SO4]A:1268	`5`	`1`	`184`	`f`	A	x,y,z	`1_555`	`12`	`5`	`8160`	`78.8`	`-12.2`	`0.704`	`2`	`0`	`0`	`0.304`
`6`		[SO4]A:1268	`5`	`1`	`184`	`◊`	A	-y,x,z	`3_555`	`9`	`4`	`8160`	`65.3`	`-9.8`	`0.489`	`0`	`0`	`0`	`0.228`
`7`		[CA]A:1264	`1`	`1`	`85`	`f`	A	x,y,z	`1_555`	`7`	`6`	`8160`	`45.4`	`-12.1`	`0.000`	`0`	`0`	`0`	`0.282`
`8`		A	`5`	`1`	`8160`	`x`	A	-y-1/2,x-1/2,z+1/2	`7_445`	`4`	`1`	`8160`	`23.2`	`0.0`	`0.634`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]