PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=766-70-60K)

Interfaces in PDB 3en5 crystal.
Space symmetry group: P 1. Resolution: 2.66 Å

TARGETED POLYPHARMACOLOGY: CRYSTAL STRUCTURE OF THE C-SRC KINASE DOMAIN IN COMPLEX WITH PP494, A MULTITARGETED KINASE INHIBITOR

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`39`	`14`	`12945`	`◊`	A	x,y,z	`1_555`	`39`	`12`	`12237`	`403.6`	`-1.4`	`0.711`	`7`	`6`	`0`	`0.000`
	`2`		B	`34`	`10`	`12945`	`◊`	A	x,y-1,z	`1_545`	`29`	`11`	`12237`	`315.6`	`-1.0`	`0.697`	`5`	`6`	`0`	`0.000`
	*Average:*													`359.6`	`-1.2`	`0.704`	`6`	`6`	`0`	`0.000`
2	`3`		[KS4]B:2	`23`	`1`	`542`	`f`	B	x,y,z	`1_555`	`43`	`20`	`12945`	`377.7`	`-5.3`	`0.424`	`2`	`0`	`0`	`0.100`
	`4`		[KS4]A:1	`24`	`1`	`542`	`f`	A	x,y,z	`1_555`	`42`	`18`	`12237`	`364.7`	`-5.1`	`0.378`	`2`	`0`	`0`	`0.100`
	*Average:*													`371.2`	`-5.2`	`0.401`	`2`	`0`	`0`	`0.100`
3	`5`		B	`45`	`13`	`12945`	`◊`	A	x,y-1,z-1	`1_544`	`42`	`9`	`12237`	`375.0`	`-3.7`	`0.535`	`7`	`0`	`0`	`0.000`
4	`6`		B	`38`	`10`	`12945`	`x`	B	x-1,y,z	`1_455`	`33`	`8`	`12945`	`328.5`	`-1.2`	`0.730`	`5`	`2`	`0`	`0.000`
	`7`		A	`35`	`9`	`12237`	`x`	A	x-1,y,z	`1_455`	`36`	`11`	`12237`	`323.3`	`-2.6`	`0.516`	`7`	`0`	`0`	`0.000`
	*Average:*													`325.9`	`-1.9`	`0.623`	`6`	`1`	`0`	`0.000`
5	`8`		A	`9`	`3`	`12237`	`◊`	B	x-1,y+1,z	`1_465`	`6`	`2`	`12945`	`80.8`	`-0.0`	`0.691`	`1`	`3`	`0`	`0.000`
	`9`		A	`4`	`2`	`12237`	`◊`	B	x-1,y,z	`1_455`	`4`	`3`	`12945`	`54.6`	`-1.0`	`0.263`	`0`	`0`	`0`	`0.000`
	*Average:*													`67.7`	`-0.5`	`0.477`	`1`	`2`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe