PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=545-DO-K58)

Interfaces in PDB 3l16 crystal.
Space symmetry group: C 1 2 1. Resolution: 2.90 Å

DISCOVERY OF (THIENOPYRIMIDIN-2-YL)AMINOPYRIMIDINES AS POTENT, SELECTIVE, AND ORALLY AVAILABLE PAN-PI3-KINASE AND DUAL PAN-PI3- KINASE/MTOR INHIBITORS FOR THE TREATMENT OF CANCER

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`52`	`16`	`37019`	`◊`	A	-x+1,y,-z+1	`2_656`	`51`	`16`	`37019`	`533.0`	`-1.8`	`0.503`	`8`	`0`	`0`	`0.000`
`2`		[JZX]A:1	`33`	`1`	`686`	`f`	A	x,y,z	`1_555`	`62`	`27`	`37019`	`475.4`	`-2.2`	`0.159`	`5`	`0`	`0`	`0.100`
`3`		A	`54`	`17`	`37019`	`x`	A	-x+1/2,y-1/2,-z	`4_545`	`42`	`17`	`37019`	`416.7`	`-2.0`	`0.345`	`3`	`0`	`0`	`0.000`
`4`		A	`42`	`13`	`37019`	`x`	A	x,y-1,z	`1_545`	`35`	`11`	`37019`	`357.2`	`-5.8`	`0.092`	`0`	`0`	`0`	`0.000`
`5`		A	`45`	`17`	`37019`	`x`	A	-x+1/2,y-1/2,-z+1	`4_546`	`34`	`12`	`37019`	`305.6`	`-0.4`	`0.617`	`1`	`2`	`0`	`0.000`
`6`		A	`23`	`9`	`37019`	`◊`	A	-x+1,y,-z	`2_655`	`23`	`9`	`37019`	`266.8`	`-2.1`	`0.330`	`2`	`2`	`0`	`0.000`
`7`		A	`27`	`10`	`37019`	`x`	A	x-1/2,y+1/2,z	`3_455`	`23`	`10`	`37019`	`182.6`	`2.8`	`0.841`	`0`	`2`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe