PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=944-6L-P9A)

Interfaces in PDB 3r92 crystal.
Space symmetry group: I 2 2 2. Resolution: 1.58 Å

DISCOVERY OF A MACROCYCLIC O-AMINOBENZAMIDE HSP90 INHIBITOR WITH HETEROCYCLIC TETHER THAT SHOWS EXTENDED BIOMARKER ACTIVITY AND IN VIVO EFFICACY IN A MOUSE XENOGRAFT MODEL.

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`77`	`25`	`10769`	`◊`	A	-x,-y,z	`2_555`	`75`	`23`	`10769`	`775.9`	`-8.4`	`0.150`	`2`	`0`	`0`	`0.000`
`2`		[06J]A:1	`30`	`1`	`620`	`f`	A	x,y,z	`1_555`	`71`	`23`	`10769`	`461.5`	`0.8`	`0.242`	`4`	`0`	`0`	`0.100`
`3`		A	`43`	`12`	`10769`	`◊`	A	-x,y,-z	`3_555`	`43`	`12`	`10769`	`347.0`	`-2.2`	`0.454`	`4`	`0`	`0`	`0.000`
`4`		A	`32`	`9`	`10769`	`x`	A	x-1/2,-y+1/2,-z+1/2	`8_455`	`42`	`13`	`10769`	`329.9`	`-4.5`	`0.166`	`1`	`0`	`0`	`0.000`
`5`		[06J]A:1	`2`	`1`	`620`	`◊`	A	-x,-y,z	`2_555`	`3`	`1`	`10769`	`4.0`	`0.1`	`0.492`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe