PDBe < PISA < EMBL-EBI

PISA Interface List.

Interfaces in PDB 4an3 crystal.
Space symmetry group: P 61. Resolution: 2.10 Å

CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`56`	`17`	`13958`	`x`	A	-y+1,x-y+1,z+1/3	`2_665`	`72`	`21`	`13958`	`553.9`	`-3.4`	`0.443`	`6`	`1`	`0`	`0.000`
`2`		A	`51`	`16`	`13958`	`x`	A	x-y,x,z+1/6	`6_555`	`47`	`17`	`13958`	`449.3`	`-3.0`	`0.355`	`5`	`7`	`0`	`0.000`
`3`		[ATP]A:1383	`31`	`1`	`602`	`f`	A	x,y,z	`1_555`	`57`	`26`	`13958`	`415.4`	`-1.7`	`0.548`	`8`	`0`	`0`	`0.027`
`4`		[5Y0]A:1384	`26`	`1`	`584`	`f`	A	x,y,z	`1_555`	`70`	`26`	`13958`	`400.2`	`0.6`	`0.395`	`4`	`0`	`0`	`0.006`
`5`		A	`9`	`3`	`13958`	`x`	A	x-y,x,z-5/6	`6_554`	`10`	`5`	`13958`	`73.2`	`1.4`	`0.836`	`1`	`1`	`0`	`0.000`
`6`		[5Y0]A:1384	`8`	`1`	`584`	`f`	[ATP]A:1383	x,y,z	`1_555`	`7`	`1`	`602`	`61.4`	`-2.1`	`0.169`	`0`	`0`	`0`	`0.011`
`7`		[ATP]A:1383	`6`	`1`	`602`	`f`	[MG]A:1382	x,y,z	`1_555`	`1`	`1`	`98`	`34.8`	`-5.5`	`0.000`	`0`	`0`	`0`	`0.028`
`8`		[MG]A:1382	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`8`	`6`	`13958`	`33.4`	`-4.0`	`0.000`	`0`	`0`	`0`	`0.021`
`9`		A	`3`	`2`	`13958`	`x`	A	x,y,z-1	`1_554`	`5`	`3`	`13958`	`33.0`	`1.4`	`0.793`	`1`	`0`	`0`	`0.000`
`10`		[5Y0]A:1384	`6`	`1`	`584`	`f`	[MG]A:1382	x,y,z	`1_555`	`1`	`1`	`98`	`12.7`	`-1.5`	`0.000`	`0`	`0`	`0`	`0.008`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
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