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PISA Interface List.

Session Map (id=112-7B-LO1)

Interfaces in PDB 4anb crystal.
Space symmetry group: P 61. Resolution: 2.20 Å

CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`55`	`17`	`13723`	`x`	A	x-y,x,z+1/6	`6_555`	`56`	`20`	`13723`	`522.4`	`-1.2`	`0.373`	`5`	`7`	`0`	`0.000`
`2`		A	`49`	`15`	`13723`	`x`	A	-y,x-y-1,z+1/3	`2_545`	`63`	`18`	`13723`	`488.4`	`-1.4`	`0.586`	`6`	`1`	`0`	`0.000`
`3`		[ACP]A:1383	`31`	`1`	`599`	`f`	A	x,y,z	`1_555`	`61`	`26`	`13723`	`418.8`	`-2.4`	`0.508`	`7`	`0`	`0`	`0.033`
`4`		[YQY]A:1382	`26`	`1`	`569`	`f`	A	x,y,z	`1_555`	`67`	`25`	`13723`	`387.7`	`1.9`	`0.367`	`6`	`0`	`0`	`0.004`
`5`		A	`20`	`8`	`13723`	`x`	A	x-y,x,z-5/6	`6_554`	`16`	`5`	`13723`	`149.7`	`1.6`	`0.822`	`4`	`4`	`0`	`0.000`
`6`		[ACP]A:1383	`5`	`1`	`599`	`f`	[YQY]A:1382	x,y,z	`1_555`	`4`	`1`	`569`	`50.4`	`0.5`	`0.429`	`2`	`0`	`0`	`0.002`
`7`		A	`3`	`1`	`13723`	`x`	A	x,y,z-1	`1_554`	`6`	`2`	`13723`	`45.1`	`1.1`	`0.797`	`1`	`0`	`0`	`0.000`
`8`		[MG]A:1384	`1`	`1`	`98`	`f`	[ACP]A:1383	x,y,z	`1_555`	`5`	`1`	`599`	`33.3`	`-5.2`	`0.000`	`0`	`0`	`0`	`0.031`
`9`		[MG]A:1384	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`10`	`7`	`13723`	`32.8`	`-4.0`	`0.000`	`0`	`0`	`0`	`0.024`
`10`		[MG]A:1384	`1`	`1`	`98`	`f`	[YQY]A:1382	x,y,z	`1_555`	`2`	`1`	`569`	`11.4`	`-1.0`	`0.000`	`0`	`0`	`0`	`0.006`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
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