PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=141-H6-19L)

Interfaces in PDB 4epw crystal.
Space symmetry group: P 21 21 21. Resolution: 1.70 Å

DISCOVERY OF SMALL MOLECULES THAT BIND TO K-RAS AND INHIBIT SOS- MEDIATED ACTIVATION

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`52`	`14`	`8645`	`x`	A	-x-1,y-1/2,-z-1/2	`3_444`	`65`	`16`	`8645`	`570.4`	`1.0`	`0.540`	`14`	`8`	`0`	`0.000`
`2`		A	`44`	`12`	`8645`	`x`	A	x-1/2,-y+1/2,-z	`4_455`	`59`	`18`	`8645`	`436.8`	`0.2`	`0.568`	`4`	`1`	`0`	`0.000`
`3`		[GDP]A:201	`26`	`1`	`566`	`f`	A	x,y,z	`1_555`	`50`	`19`	`8645`	`361.8`	`-8.2`	`0.401`	`11`	`0`	`0`	`0.042`
`4`		A	`31`	`9`	`8645`	`x`	A	x-1,y,z	`1_455`	`35`	`8`	`8645`	`335.4`	`-1.0`	`0.383`	`5`	`1`	`0`	`0.000`
`5`		[0QV]A:203	`17`	`1`	`435`	`f`	A	x,y,z	`1_555`	`40`	`14`	`8645`	`256.4`	`-6.6`	`0.406`	`0`	`0`	`0`	`0.021`
`6`		A	`14`	`7`	`8645`	`x`	A	-x,y-1/2,-z-1/2	`3_544`	`15`	`4`	`8645`	`93.3`	`-0.4`	`0.473`	`1`	`0`	`0`	`0.000`
`7`		A	`10`	`3`	`8645`	`x`	A	x-1/2,-y-1/2,-z	`4_445`	`11`	`5`	`8645`	`79.3`	`0.4`	`0.633`	`0`	`0`	`0`	`0.000`
`8`		[MG]A:202	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`16`	`9`	`8645`	`50.4`	`-6.7`	`0.000`	`0`	`0`	`0`	`0.022`
`9`		A	`6`	`3`	`8645`	`x`	A	x,y-1,z	`1_545`	`5`	`3`	`8645`	`46.7`	`0.9`	`0.778`	`0`	`0`	`0`	`0.000`
`10`		[MG]A:202	`1`	`1`	`98`	`f`	[GDP]A:201	x,y,z	`1_555`	`4`	`1`	`566`	`30.4`	`-4.6`	`0.000`	`0`	`0`	`0`	`0.015`
`11`		[0QV]A:203	`3`	`1`	`435`	`◊`	A	x-1,y,z	`1_455`	`6`	`2`	`8645`	`29.8`	`-0.0`	`0.726`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe