PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=847-45-GD8)

Interfaces in PDB 4qoc crystal.
Space symmetry group: P 21 21 21. Resolution: 1.70 Å

CRYSTAL STRUCTURE OF COMPOUND 16 BOUND TO MDM2(17-111), {(3R,5R,6S)-5- (3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2- (PYRROLIDIN-1-YLSULFONYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		E	`74`	`17`	`5905`	`◊`	G	-x-1/2,-y,z-1/2	`2_454`	`62`	`16`	`5954`	`617.2`	`-4.3`	`0.458`	`5`	`0`	`0`	`0.000`
2	`2`		K	`74`	`17`	`6178`	`◊`	A	x-1,y,z	`1_455`	`61`	`18`	`5765`	`609.5`	`-4.4`	`0.416`	`7`	`1`	`0`	`0.030`
	`3`		G	`72`	`16`	`5954`	`◊`	C	x,y,z	`1_555`	`62`	`16`	`5885`	`570.6`	`-7.3`	`0.265`	`5`	`0`	`0`	`0.030`
	`4`		E	`54`	`13`	`5905`	`◊`	C	x,y,z	`1_555`	`62`	`13`	`5885`	`547.8`	`-5.3`	`0.350`	`7`	`0`	`0`	`0.030`
	`5`		I	`56`	`14`	`5720`	`◊`	A	x-1,y,z	`1_455`	`61`	`14`	`5765`	`524.9`	`-5.1`	`0.308`	`8`	`0`	`0`	`0.030`
	*Average:*													`563.2`	`-5.5`	`0.335`	`7`	`0`	`0`	`0.030`
3	`6`		[35T]K:201	`31`	`1`	`755`	`f`	K	x,y,z	`1_555`	`53`	`18`	`6178`	`440.7`	`-12.3`	`0.373`	`2`	`0`	`0`	`0.100`
4	`7`		[35T]E:201	`30`	`1`	`754`	`f`	E	x,y,z	`1_555`	`54`	`19`	`5905`	`433.8`	`-12.4`	`0.377`	`1`	`0`	`0`	`0.100`
	`8`		[35T]A:201	`31`	`1`	`749`	`f`	A	x,y,z	`1_555`	`53`	`19`	`5765`	`421.0`	`-11.8`	`0.397`	`2`	`0`	`0`	`0.100`
	`9`		[35T]I:201	`29`	`1`	`750`	`f`	I	x,y,z	`1_555`	`54`	`19`	`5720`	`418.0`	`-12.4`	`0.353`	`2`	`0`	`0`	`0.100`
	`10`		[35T]G:201	`27`	`1`	`758`	`f`	G	x,y,z	`1_555`	`47`	`17`	`5954`	`414.6`	`-12.8`	`0.311`	`2`	`0`	`0`	`0.100`
	`11`		[35T]C:201	`28`	`1`	`745`	`f`	C	x,y,z	`1_555`	`48`	`18`	`5885`	`408.2`	`-11.8`	`0.352`	`2`	`0`	`0`	`0.100`
	*Average:*													`419.1`	`-12.2`	`0.358`	`2`	`0`	`0`	`0.100`
5	`12`		C	`48`	`13`	`5885`	`◊`	A	x,y,z	`1_555`	`47`	`13`	`5765`	`429.7`	`2.4`	`0.832`	`8`	`6`	`0`	`0.000`
6	`13`		K	`37`	`11`	`6178`	`x`	C	x-1,y,z	`1_455`	`35`	`8`	`5885`	`380.8`	`0.1`	`0.481`	`2`	`1`	`0`	`0.000`
	`14`		I	`41`	`9`	`5720`	`x`	I	x-1/2,-y-1/2,-z	`4_445`	`39`	`13`	`5720`	`361.8`	`-1.1`	`0.506`	`3`	`0`	`0`	`0.000`
	`15`		G	`30`	`8`	`5954`	`x`	A	x,y,z	`1_555`	`29`	`9`	`5765`	`283.7`	`-1.5`	`0.390`	`0`	`0`	`0`	`0.000`
	`16`		C	`16`	`7`	`5885`	`x`	G	-x,y-1/2,-z-1/2	`3_544`	`24`	`8`	`5954`	`202.4`	`-1.7`	`0.339`	`2`	`0`	`0`	`0.000`
	*Average:*													`307.2`	`-1.0`	`0.429`	`2`	`0`	`0`	`0.000`
7	`17`		K	`33`	`11`	`6178`	`◊`	E	x,y,z	`1_555`	`28`	`11`	`5905`	`335.4`	`-1.1`	`0.561`	`6`	`2`	`0`	`0.000`
	`18`		I	`23`	`9`	`5720`	`◊`	G	x,y,z	`1_555`	`20`	`9`	`5954`	`222.2`	`-0.6`	`0.601`	`0`	`0`	`0`	`0.000`
	`19`		C	`17`	`8`	`5885`	`◊`	A	x-1,y,z	`1_455`	`15`	`8`	`5765`	`172.8`	`-2.2`	`0.347`	`1`	`1`	`0`	`0.000`
	*Average:*													`243.5`	`-1.3`	`0.503`	`2`	`1`	`0`	`0.000`
8	`20`		K	`37`	`14`	`6178`	`◊`	I	-x-1/2,-y,z-1/2	`2_454`	`40`	`12`	`5720`	`307.6`	`-1.8`	`0.476`	`1`	`0`	`0`	`0.000`
9	`21`		E	`27`	`10`	`5905`	`x`	E	x-1/2,-y-1/2,-z-1	`4_444`	`28`	`7`	`5905`	`273.8`	`-1.4`	`0.396`	`3`	`0`	`0`	`0.000`
10	`22`		I	`31`	`9`	`5720`	`◊`	K	-x-1,y-1/2,-z-1/2	`3_444`	`33`	`11`	`6178`	`266.2`	`3.6`	`0.891`	`2`	`0`	`0`	`0.000`
	`23`		E	`26`	`9`	`5905`	`◊`	G	-x,y-1/2,-z-1/2	`3_544`	`24`	`8`	`5954`	`203.2`	`1.6`	`0.795`	`2`	`0`	`0`	`0.000`
	*Average:*													`234.7`	`2.6`	`0.843`	`2`	`0`	`0`	`0.000`
11	`24`		K	`24`	`5`	`6178`	`◊`	G	-x-1/2,-y,z-1/2	`2_454`	`22`	`6`	`5954`	`201.3`	`-0.3`	`0.606`	`3`	`2`	`0`	`0.000`
12	`25`		E	`20`	`5`	`5905`	`◊`	A	x-1,y,z	`1_455`	`22`	`5`	`5765`	`194.2`	`0.7`	`0.732`	`2`	`2`	`0`	`0.000`
	`26`		I	`21`	`5`	`5720`	`◊`	C	x,y,z	`1_555`	`23`	`5`	`5885`	`186.3`	`0.1`	`0.675`	`2`	`1`	`0`	`0.000`
	*Average:*													`190.2`	`0.4`	`0.703`	`2`	`2`	`0`	`0.000`
13	`27`		A	`16`	`6`	`5765`	`◊`	K	-x,y-1/2,-z-1/2	`3_544`	`21`	`6`	`6178`	`185.9`	`-2.9`	`0.220`	`1`	`1`	`0`	`0.000`
14	`28`		K	`18`	`4`	`6178`	`◊`	[35T]A:201	x-1,y,z	`1_455`	`12`	`1`	`749`	`151.6`	`-1.7`	`0.564`	`1`	`0`	`0`	`0.003`
	`29`		[35T]E:201	`13`	`1`	`754`	`◊`	C	x,y,z	`1_555`	`15`	`3`	`5885`	`131.6`	`-1.0`	`0.655`	`0`	`0`	`0`	`0.003`
	`30`		[35T]I:201	`12`	`1`	`750`	`◊`	A	x-1,y,z	`1_455`	`15`	`3`	`5765`	`129.5`	`-0.9`	`0.630`	`0`	`0`	`0`	`0.003`
	`31`		[35T]C:201	`12`	`1`	`745`	`◊`	G	x,y,z	`1_555`	`15`	`3`	`5954`	`128.4`	`-0.5`	`0.651`	`1`	`0`	`0`	`0.003`
	*Average:*													`135.3`	`-1.0`	`0.625`	`1`	`0`	`0`	`0.003`
15	`32`		G	`15`	`5`	`5954`	`◊`	A	x-1,y,z	`1_455`	`12`	`5`	`5765`	`125.4`	`-0.3`	`0.591`	`0`	`0`	`0`	`0.000`
	`33`		K	`10`	`4`	`6178`	`◊`	C	x,y,z	`1_555`	`10`	`5`	`5885`	`122.8`	`0.3`	`0.606`	`0`	`0`	`0`	`0.000`
	*Average:*													`124.1`	`-0.0`	`0.599`	`0`	`0`	`0`	`0.000`
16	`34`		E	`10`	`3`	`5905`	`◊`	I	-x-1/2,-y,z-1/2	`2_454`	`11`	`4`	`5720`	`104.1`	`-1.5`	`0.366`	`0`	`0`	`0`	`0.000`
17	`35`		E	`9`	`3`	`5905`	`◊`	[35T]G:201	-x-1/2,-y,z-1/2	`2_454`	`7`	`1`	`758`	`53.3`	`-0.5`	`0.525`	`0`	`0`	`0`	`0.000`
18	`36`		[35T]K:201	`3`	`1`	`755`	`◊`	I	-x-1/2,-y,z-1/2	`2_454`	`8`	`3`	`5720`	`42.7`	`-0.8`	`0.433`	`0`	`0`	`0`	`0.000`
19	`37`		K	`3`	`1`	`6178`	`◊`	G	x,y,z	`1_555`	`1`	`1`	`5954`	`17.8`	`-0.1`	`0.321`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe