PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=433-69-D41)

Interfaces in PDB 5dwr crystal.
Space symmetry group: P 65. Resolution: 2.00 Å

IDENTIFICATION OF N-(4-((1R,3S,5S)-3-AMINO-5-METHYLCYCLOHEXYL)PYRIDIN- 3-YL)-6-(2,6-DIFLUOROPHENYL)-5-FLUOROPICOLINAMIDE (PIM447), A POTENT AND SELECTIVE PROVIRAL INSERTION SITE OF MOLONEY MURINE LEUKEMIA (PIM) 1,2 AND 3 KINASE INHIBITOR IN CLINICAL TRIALS FOR HEMATOLOGICAL MALIGNANCIES

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`81`	`24`	`13086`	`x`	A	-y-1,x-y,z-1/3	`3_454`	`69`	`16`	`13086`	`673.8`	`-1.9`	`0.545`	`6`	`5`	`0`	`0.000`
`2`		[5H7]A:401	`31`	`1`	`589`	`f`	A	x,y,z	`1_555`	`56`	`20`	`13086`	`422.5`	`1.4`	`0.206`	`2`	`0`	`0`	`0.000`
`3`		A	`36`	`9`	`13086`	`x`	A	x-y,x,z-1/6	`2_554`	`41`	`13`	`13086`	`349.0`	`-1.3`	`0.505`	`5`	`1`	`0`	`0.000`
`4`		A	`1`	`1`	`13086`	`x`	A	x-y,x+1,z-1/6	`2_564`	`1`	`1`	`13086`	`4.2`	`-0.1`	`0.460`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

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PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe