PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=566-DP-599)

Interfaces in PDB 5hic crystal.
Space symmetry group: I 2 3. Resolution: 2.60 Å

EGFR KINASE DOMAIN MUTANT "TMLR" WITH A IMIDAZOPYRIDINYL- AMINOPYRIMIDINE INHIBITOR

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`120`	`33`	`15562`	`◊`	A	-x-1,-y,z	`2_455`	`118`	`33`	`15562`	`1146.5`	`-4.1`	`0.648`	`14`	`8`	`0`	`0.000`
`2`		A	`109`	`30`	`15562`	`x`	A	-z-1/2,x+1/2,-y-1/2	`20_454`	`99`	`26`	`15562`	`1011.2`	`-14.8`	`0.077`	`7`	`2`	`0`	`0.000`
`3`		[63N]A:1102	`30`	`1`	`586`	`f`	A	x,y,z	`1_555`	`63`	`22`	`15562`	`427.9`	`1.0`	`0.334`	`3`	`0`	`0`	`0.002`
`4`		A	`39`	`11`	`15562`	`◊`	A	x,-y,-z	`4_555`	`39`	`11`	`15562`	`333.4`	`-0.6`	`0.669`	`8`	`0`	`0`	`0.000`
`5`		A	`32`	`10`	`15562`	`◊`	A	-x-1,y,-z	`3_455`	`32`	`10`	`15562`	`248.7`	`4.4`	`0.944`	`4`	`2`	`0`	`0.000`
`6`		[SO4]A:1101	`5`	`1`	`185`	`f`	A	x,y,z	`1_555`	`17`	`7`	`15562`	`93.5`	`-14.6`	`0.665`	`2`	`0`	`0`	`0.098`
`7`		A	`4`	`1`	`15562`	`x`	A	z-1/2,-x-1/2,-y-1/2	`18_444`	`2`	`1`	`15562`	`32.3`	`0.4`	`0.741`	`0`	`0`	`0`	`0.000`
`8`		A	`1`	`1`	`15562`	`x`	A	-z-1/2,-x-1/2,y-1/2	`19_444`	`1`	`1`	`15562`	`3.4`	`0.1`	`0.583`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe