PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=522-DC-65C)

Interfaces in PDB 5wal crystal.
Space symmetry group: P 21 21 21. Resolution: 2.45 Å

IDENTIFICATION OF AN IMIDAZOPYRIDINE SCAFFOLD TO GENERATE POTENT AND SELECTIVE TYK2 INHIBITORS THAT DEMONSTRATE ACTIVITY IN AN IN VIVO PSORIASIS MODEL

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`84`	`24`	`13834`	`x`	A	x-1,y,z	`1_455`	`62`	`19`	`13834`	`601.3`	`-7.0`	`0.191`	`1`	`0`	`0`	`0.000`
`2`		A	`70`	`20`	`13834`	`x`	A	-x-1,y-1/2,-z+1/2	`3_445`	`66`	`23`	`13834`	`591.4`	`-4.9`	`0.298`	`1`	`0`	`0`	`0.000`
`3`		A	`50`	`14`	`13834`	`x`	A	x-1/2,-y+1/2,-z	`4_455`	`45`	`13`	`13834`	`423.5`	`-4.2`	`0.286`	`1`	`0`	`0`	`0.000`
`4`		[9ZS]A:1201	`22`	`1`	`527`	`f`	A	x,y,z	`1_555`	`46`	`22`	`13834`	`353.7`	`-7.9`	`0.391`	`1`	`0`	`0`	`0.100`
`5`		A	`30`	`12`	`13834`	`x`	A	-x,y-1/2,-z+1/2	`3_545`	`34`	`10`	`13834`	`323.1`	`-0.4`	`0.576`	`3`	`4`	`0`	`0.000`
`6`		A	`3`	`1`	`13834`	`x`	A	x-1/2,-y-1/2,-z	`4_445`	`4`	`2`	`13834`	`30.7`	`0.1`	`0.634`	`0`	`0`	`0`	`0.000`
`7`		A	`3`	`2`	`13834`	`x`	A	-x-1/2,-y,z-1/2	`2_454`	`2`	`1`	`13834`	`19.9`	`0.9`	`0.866`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe