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PISA Interface List.

Session Map (id=624-6L-FFI)

Interfaces in PDB 6bn5 crystal.
Space symmetry group: P 1 21 1. Resolution: 2.22 Å

NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 F285S IN COMPLEX WITH ALLOSTERIC INHIBITOR JLR-2

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`65`	`21`	`20512`	`◊`	A	x,y,z	`1_555`	`67`	`25`	`21162`	`575.5`	`-2.4`	`0.472`	`9`	`0`	`0`	`0.000`
2	`2`		[DZJ]B:601	`23`	`1`	`513`	`f`	B	x,y,z	`1_555`	`46`	`15`	`20512`	`324.6`	`-6.9`	`0.422`	`2`	`0`	`0`	`0.100`
	`3`		[DZJ]A:601	`22`	`1`	`516`	`f`	A	x,y,z	`1_555`	`45`	`14`	`21162`	`322.5`	`-7.3`	`0.369`	`1`	`0`	`0`	`0.100`
	*Average:*													`323.5`	`-7.1`	`0.395`	`2`	`0`	`0`	`0.100`
3	`4`		A	`37`	`12`	`21162`	`◊`	B	-x+2,y-1/2,-z+1	`2_746`	`37`	`11`	`20512`	`306.5`	`0.4`	`0.665`	`5`	`6`	`0`	`0.000`
	`5`		A	`38`	`10`	`21162`	`◊`	B	-x+2,y-1/2,-z	`2_745`	`34`	`11`	`20512`	`290.3`	`0.6`	`0.684`	`4`	`6`	`0`	`0.000`
	*Average:*													`298.4`	`0.5`	`0.675`	`5`	`6`	`0`	`0.000`
4	`6`		A	`25`	`8`	`21162`	`x`	A	x-1,y,z	`1_455`	`27`	`10`	`21162`	`238.1`	`-1.1`	`0.365`	`1`	`0`	`0`	`0.000`
5	`7`		A	`20`	`6`	`21162`	`◊`	B	x,y,z-1	`1_554`	`25`	`5`	`20512`	`214.4`	`-2.7`	`0.218`	`1`	`0`	`0`	`0.000`
6	`8`		A	`18`	`7`	`21162`	`x`	A	x,y,z-1	`1_554`	`24`	`7`	`21162`	`169.3`	`1.3`	`0.757`	`1`	`0`	`0`	`0.000`
	`9`		B	`13`	`4`	`20512`	`x`	B	x,y,z-1	`1_554`	`12`	`5`	`20512`	`122.8`	`0.6`	`0.700`	`1`	`0`	`0`	`0.000`
	*Average:*													`146.1`	`1.0`	`0.729`	`1`	`0`	`0`	`0.000`
7	`10`		A	`18`	`7`	`21162`	`◊`	B	-x+3,y-1/2,-z+1	`2_846`	`18`	`5`	`20512`	`163.3`	`-1.6`	`0.360`	`2`	`0`	`0`	`0.000`
8	`11`		B	`17`	`8`	`20512`	`x`	B	x-1,y,z	`1_455`	`11`	`4`	`20512`	`112.1`	`-0.2`	`0.574`	`1`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe