PDBe < PISA < EMBL-EBI

PISA Interface List.

Interfaces in PDB 6g8x crystal.
Space symmetry group: P 1 21 1. Resolution: 1.76 Å

FRAGMENT-BASED DISCOVERY OF A HIGHLY POTENT, ORALLY BIOAVAILABLE INHIBITOR WHICH MODULATES THE PHOSPHORYLATION AND CATALYTIC ACTIVITY OF ERK1/2

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`50`	`14`	`16546`	`x`	A	x-1,y,z-1	`1_454`	`55`	`17`	`16546`	`488.6`	`-2.2`	`0.369`	`4`	`0`	`0`	`0.000`
`2`		A	`45`	`12`	`16546`	`x`	A	x-1,y,z	`1_455`	`45`	`13`	`16546`	`452.3`	`-4.6`	`0.236`	`7`	`0`	`0`	`0.000`
`3`		A	`45`	`12`	`16546`	`x`	A	-x,y-1/2,-z+1	`2_546`	`43`	`15`	`16546`	`440.3`	`-6.5`	`0.092`	`1`	`1`	`0`	`0.000`
`4`		[EQT]A:403	`11`	`1`	`301`	`f`	A	x,y,z	`1_555`	`32`	`11`	`16546`	`211.3`	`-2.4`	`0.415`	`0`	`0`	`0`	`0.007`
`5`		[EQT]A:404	`11`	`1`	`302`	`f`	A	x,y,z	`1_555`	`28`	`14`	`16546`	`203.5`	`-1.0`	`0.405`	`2`	`0`	`0`	`0.005`
`6`		A	`18`	`5`	`16546`	`x`	A	-x+1,y-1/2,-z+2	`2_647`	`13`	`7`	`16546`	`148.6`	`-1.4`	`0.135`	`0`	`0`	`0`	`0.000`
`7`		A	`20`	`7`	`16546`	`x`	A	x,y,z-1	`1_554`	`13`	`5`	`16546`	`137.7`	`0.8`	`0.683`	`2`	`0`	`0`	`0.000`
`8`		[SO4]A:401	`5`	`1`	`186`	`f`	A	x,y,z	`1_555`	`13`	`7`	`16546`	`103.2`	`-14.4`	`0.928`	`8`	`0`	`0`	`0.048`
`9`		[SO4]A:402	`5`	`1`	`186`	`f`	A	x,y,z	`1_555`	`13`	`4`	`16546`	`92.9`	`-13.3`	`0.886`	`4`	`0`	`0`	`0.040`
`10`		A	`5`	`2`	`16546`	`x`	A	-x+1,y-1/2,-z+1	`2_646`	`6`	`2`	`16546`	`27.7`	`0.4`	`0.727`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe