PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=711-D2-AD5)

Interfaces in PDB 6g92 crystal.
Space symmetry group: P 1 21 1. Resolution: 1.99 Å

FRAGMENT-BASED DISCOVERY OF A HIGHLY POTENT, ORALLY BIOAVAILABLE INHIBITOR WHICH MODULATES THE PHOSPHORYLATION AND CATALYTIC ACTIVITY OF ERK1/2

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`59`	`20`	`16826`	`x`	A	x-1,y,z-1	`1_454`	`59`	`19`	`16826`	`563.1`	`-3.9`	`0.291`	`5`	`1`	`0`	`0.000`
`2`		A	`53`	`13`	`16826`	`x`	A	x-1,y,z	`1_455`	`52`	`17`	`16826`	`522.0`	`-3.6`	`0.343`	`7`	`0`	`0`	`0.000`
`3`		A	`44`	`11`	`16826`	`x`	A	-x,y-1/2,-z+1	`2_546`	`43`	`15`	`16826`	`427.6`	`-5.7`	`0.131`	`1`	`1`	`0`	`0.000`
`4`		[ERZ]A:404	`15`	`1`	`397`	`f`	A	x,y,z	`1_555`	`39`	`16`	`16826`	`260.1`	`4.7`	`0.389`	`1`	`0`	`0`	`0.000`
`5`		A	`20`	`7`	`16826`	`x`	A	x,y,z-1	`1_554`	`16`	`5`	`16826`	`149.8`	`0.0`	`0.610`	`2`	`0`	`0`	`0.000`
`6`		A	`14`	`4`	`16826`	`x`	A	-x+1,y-1/2,-z+2	`2_647`	`9`	`5`	`16826`	`132.2`	`-2.7`	`0.046`	`0`	`0`	`0`	`0.000`
`7`		[SO4]A:401	`5`	`1`	`186`	`f`	A	x,y,z	`1_555`	`13`	`6`	`16826`	`100.8`	`-13.9`	`0.922`	`4`	`0`	`0`	`0.061`
`8`		[SO4]A:403	`4`	`1`	`186`	`f`	A	x,y,z	`1_555`	`8`	`4`	`16826`	`68.3`	`-7.6`	`0.862`	`1`	`0`	`0`	`0.031`
`9`		[SO4]A:402	`4`	`1`	`186`	`f`	A	x,y,z	`1_555`	`7`	`3`	`16826`	`45.7`	`-4.5`	`0.951`	`1`	`0`	`0`	`0.019`
`10`		[SO4]A:403	`4`	`1`	`186`	`◊`	A	-x,y-1/2,-z+1	`2_546`	`7`	`3`	`16826`	`34.4`	`-4.8`	`0.489`	`0`	`0`	`0`	`0.000`
`11`		A	`5`	`2`	`16826`	`x`	A	-x+1,y-1/2,-z+1	`2_646`	`6`	`2`	`16826`	`26.0`	`0.5`	`0.731`	`0`	`0`	`0`	`0.000`
`12`		[SO4]A:402	`2`	`1`	`186`	`f`	[SO4]A:401	x,y,z	`1_555`	`1`	`1`	`186`	`6.1`	`-1.5`	`0.876`	`0`	`0`	`0`	`0.006`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
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