PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=251-5L-13C)

Interfaces in PDB 6u8b crystal.
Space symmetry group: P 1. Resolution: 1.26 Å

DISCOVERY AND OPTIMIZATION OF SALICYCLIC ACID-DERIVED SULFONAMIDE INHIBITORS OF THE WDR5:MYC PROTEIN-PROTEIN INTERACTION

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`71`	`20`	`12587`	`◊`	A	x,y,z	`1_555`	`78`	`28`	`12703`	`682.4`	`0.4`	`0.688`	`11`	`2`	`0`	`0.000`
	`2`		B	`74`	`23`	`12587`	`◊`	A	x-1,y,z	`1_455`	`76`	`23`	`12703`	`675.4`	`1.9`	`0.786`	`7`	`2`	`0`	`0.000`
	*Average:*													`678.9`	`1.1`	`0.737`	`9`	`2`	`0`	`0.000`
2	`3`		[Q1M]A:401	`23`	`1`	`527`	`f`	A	x,y,z	`1_555`	`40`	`14`	`12703`	`316.8`	`-9.7`	`0.250`	`2`	`0`	`0`	`0.100`
	`4`		[Q1M]B:401	`24`	`1`	`529`	`f`	B	x,y,z	`1_555`	`37`	`14`	`12587`	`316.2`	`-9.4`	`0.234`	`2`	`0`	`0`	`0.100`
	*Average:*													`316.5`	`-9.5`	`0.242`	`2`	`0`	`0`	`0.100`
3	`5`		B	`30`	`8`	`12587`	`x`	B	x,y-1,z	`1_545`	`28`	`10`	`12587`	`258.2`	`-0.8`	`0.526`	`1`	`0`	`0`	`0.000`
4	`6`		B	`27`	`13`	`12587`	`x`	B	x-1,y,z	`1_455`	`25`	`8`	`12587`	`254.5`	`-1.7`	`0.379`	`1`	`0`	`0`	`0.000`
	`7`		A	`27`	`13`	`12703`	`x`	A	x-1,y,z	`1_455`	`25`	`8`	`12703`	`254.3`	`-1.7`	`0.413`	`1`	`0`	`0`	`0.000`
	*Average:*													`254.4`	`-1.7`	`0.396`	`1`	`0`	`0`	`0.000`
5	`8`		A	`33`	`13`	`12703`	`x`	A	x,y-1,z	`1_545`	`19`	`6`	`12703`	`239.4`	`1.3`	`0.782`	`2`	`1`	`0`	`0.000`
6	`9`		A	`12`	`6`	`12703`	`◊`	B	x,y,z-1	`1_554`	`16`	`9`	`12587`	`117.5`	`1.8`	`0.831`	`3`	`2`	`0`	`0.000`
	`10`		B	`12`	`6`	`12587`	`◊`	A	x-1,y,z+1	`1_456`	`16`	`9`	`12703`	`110.7`	`1.9`	`0.841`	`3`	`2`	`0`	`0.000`
	*Average:*													`114.1`	`1.8`	`0.836`	`3`	`2`	`0`	`0.000`
7	`11`		B	`7`	`3`	`12587`	`◊`	A	x-1,y+1,z	`1_465`	`12`	`5`	`12703`	`105.6`	`-2.0`	`0.109`	`0`	`0`	`0`	`0.000`
8	`12`		[Q1M]B:401	`7`	`1`	`529`	`◊`	A	x,y,z	`1_555`	`11`	`4`	`12703`	`63.4`	`-0.4`	`0.635`	`0`	`0`	`0`	`0.000`
	`13`		B	`8`	`4`	`12587`	`◊`	[Q1M]A:401	x-1,y,z	`1_455`	`5`	`1`	`527`	`57.9`	`-0.2`	`0.620`	`0`	`0`	`0`	`0.000`
	*Average:*													`60.6`	`-0.3`	`0.627`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe