PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=641-H9-CPC)

Interfaces in PDB 6uoz crystal.
Space symmetry group: P 1. Resolution: 1.53 Å

DISCOVERY OF FRAGMENT-INSPIRED HETEROCYCLIC BENZENESULFONMIDES AS INHIBITORS OF THE WDR5-MYC INTERACTION

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		A	`61`	`20`	`11652`	`◊`	B	x-1,y-1,z-1	`1_444`	`61`	`21`	`11599`	`491.3`	`2.1`	`0.836`	`7`	`4`	`0`	`0.000`
2	`2`		B	`44`	`11`	`11599`	`◊`	A	x,y,z	`1_555`	`49`	`13`	`11652`	`431.9`	`-3.5`	`0.375`	`3`	`3`	`0`	`0.000`
	`3`		A	`48`	`14`	`11652`	`◊`	B	x-1,y,z	`1_455`	`35`	`8`	`11599`	`349.7`	`-1.8`	`0.498`	`3`	`2`	`0`	`0.000`
	*Average:*													`390.8`	`-2.6`	`0.437`	`3`	`3`	`0`	`0.000`
3	`4`		[QF1]B:401	`27`	`1`	`598`	`f`	B	x,y,z	`1_555`	`42`	`14`	`11599`	`377.9`	`-5.7`	`0.432`	`3`	`0`	`0`	`0.100`
	`5`		[QF1]A:401	`26`	`1`	`600`	`f`	A	x,y,z	`1_555`	`43`	`14`	`11652`	`370.0`	`-5.5`	`0.410`	`2`	`0`	`0`	`0.100`
	*Average:*													`373.9`	`-5.6`	`0.421`	`3`	`0`	`0`	`0.100`
4	`6`		A	`25`	`11`	`11652`	`x`	A	x-1,y,z	`1_455`	`23`	`7`	`11652`	`228.4`	`-2.5`	`0.306`	`0`	`0`	`0`	`0.000`
	`7`		B	`24`	`11`	`11599`	`x`	B	x-1,y,z	`1_455`	`21`	`7`	`11599`	`213.7`	`-2.6`	`0.296`	`1`	`0`	`0`	`0.000`
	*Average:*													`221.1`	`-2.6`	`0.301`	`1`	`0`	`0`	`0.000`
5	`8`		A	`20`	`10`	`11652`	`◊`	B	x,y,z-1	`1_554`	`10`	`6`	`11599`	`111.3`	`1.7`	`0.851`	`3`	`2`	`0`	`0.000`
	`9`		A	`13`	`7`	`11652`	`◊`	B	x-1,y,z-1	`1_454`	`17`	`10`	`11599`	`104.9`	`1.5`	`0.834`	`3`	`2`	`0`	`0.000`
	*Average:*													`108.1`	`1.6`	`0.843`	`3`	`2`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe