N-methyl-L-phenylalanine
A protein modification that effectively converts an L-phenylalanine residue to N-methyl-L-phenylalanine.
Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
Exact Synonyms
(2S)-2-methylamino-3-phenylpropanoic acid
MOD_RES N-methylphenylalanine
N-methyl-L-phenylalanine
N-methylated L-phenylalanine
N-methylphenylalanine
NMe1Phe
Related Synonyms
Methyl
Methylation
class Information
DiffAvg
14.03
DiffFormula
C 1 H 2 N 0 O 0
DiffMono
14.01565
Formula
C 10 H 11 N 1 O 1
has_dbxref
uniprot.ptm:PTM-0218
has_obo_namespace
PSI-MOD
in_subset
MassAvg
161.2
MassMono
161.08406
Origin
F
Source
natural
TermSpec
N-term