{
  "iri" : "http://purl.obolibrary.org/obo/CL_0000553",
  "lang" : "en",
  "description" : [ "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).", "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ],
  "synonyms" : [ "CFU-Meg", "Meg-CFC", "MkP", "colony-forming unit-megakaryocyte", "megacaryoblast", "megacaryocyte progenitor cell", "megakaryoblast", "megakaryocytic progenitor cell", "promegacaryocyte", "promegakaryocyte" ],
  "annotation" : {
    "has_dbxref" : [ "BTO:0001164", "CALOHA:TS-0610", "FMA:84235", "MESH:D055016" ],
    "present in taxon" : [ "http://purl.obolibrary.org/obo/NCBITaxon_9606" ]
  },
  "label" : "megakaryocyte progenitor cell",
  "ontology_name" : "rbo",
  "ontology_prefix" : "RBO",
  "ontology_iri" : "http://purl.obolibrary.org/obo/rbo.owl",
  "is_obsolete" : false,
  "term_replaced_by" : null,
  "is_defining_ontology" : false,
  "has_children" : false,
  "is_root" : false,
  "short_form" : "CL_0000553",
  "obo_id" : "CL:0000553",
  "in_subset" : [ "human_reference_atlas" ],
  "obo_definition_citation" : [ {
    "definition" : "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).",
    "oboXrefs" : [ {
      "database" : "GOC",
      "id" : "dsd",
      "description" : null,
      "url" : null
    }, {
      "database" : "GOC",
      "id" : "tfm",
      "description" : null,
      "url" : null
    }, {
      "database" : "ISBN",
      "id" : "0721601464",
      "description" : null,
      "url" : "https://www.worldcat.org/search?q=bn%3A0721601464"
    } ]
  } ],
  "obo_xref" : [ {
    "database" : "BTO",
    "id" : "0001164",
    "description" : null,
    "url" : "http://purl.obolibrary.org/obo/BTO_0001164"
  }, {
    "database" : "CALOHA",
    "id" : "TS-0610",
    "description" : null,
    "url" : null
  }, {
    "database" : "FMA",
    "id" : "84235",
    "description" : null,
    "url" : "https://www.ebi.ac.uk/ols4/ontologies/fma/terms?obo_id=FMA:84235"
  }, {
    "database" : "MESH",
    "id" : "D055016",
    "description" : null,
    "url" : "http://id.nlm.nih.gov/mesh/D055016"
  } ],
  "obo_synonym" : [ {
    "name" : "CFU-Meg",
    "scope" : "hasExactSynonym",
    "type" : null,
    "xrefs" : [ {
      "database" : "PMID",
      "id" : "11722431",
      "description" : null,
      "url" : "http://www.ncbi.nlm.nih.gov/pubmed/11722431"
    }, {
      "database" : "PMID",
      "id" : "12482498",
      "description" : null,
      "url" : "http://www.ncbi.nlm.nih.gov/pubmed/12482498"
    } ]
  }, {
    "name" : "Meg-CFC",
    "scope" : "hasExactSynonym",
    "type" : null,
    "xrefs" : [ {
      "database" : "PMCID",
      "id" : "PMC1794060",
      "description" : null,
      "url" : "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794060"
    } ]
  }, {
    "name" : "MkP",
    "scope" : "hasExactSynonym",
    "type" : null,
    "xrefs" : [ {
      "database" : "PMID",
      "id" : "21116988",
      "description" : null,
      "url" : "http://www.ncbi.nlm.nih.gov/pubmed/21116988"
    } ]
  }, {
    "name" : "megakaryocytic progenitor cell",
    "scope" : "hasExactSynonym",
    "type" : null,
    "xrefs" : [ {
      "database" : "PMID",
      "id" : "12482498",
      "description" : null,
      "url" : "http://www.ncbi.nlm.nih.gov/pubmed/12482498"
    } ]
  } ],
  "is_preferred_root" : false,
  "_links" : {
    "self" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553?lang=en"
    },
    "parents" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/parents"
    },
    "ancestors" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/ancestors"
    },
    "hierarchicalParents" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/hierarchicalParents"
    },
    "hierarchicalAncestors" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/hierarchicalAncestors"
    },
    "jstree" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/jstree"
    },
    "graph" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/graph"
    },
    "lacks_plasma_membrane_part" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_4030046"
    },
    "capable_of" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FRO_0002215"
    },
    "develops_from" : {
      "href" : "https://www.ebi.ac.uk/ols4/api/ontologies/rbo/terms/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000553/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FRO_0002202"
    }
  }
}