guanyl-nucleotide exchange factor activityImported
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Defined bygo
class Information
alternative label
- GDP-dissociation stimulator activity
- GDS
- GEF
- guanyl-nucleotide release factor activity
- guanyl-nucleotide releasing factor
has related match
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- Reactome:REACT_94237
- Reactome:REACT_24016
- Reactome:REACT_23806
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- Reactome:REACT_12071
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- Reactome:REACT_87420
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has_obo_namespace
molecular_function
in_subset
preferred label
guanyl-nucleotide exchange factor activity
class Relations
Subclass of
Related from
enables
- DOCK4_HUMAN
- ARG33_MOUSE
- RGPS2_MOUSE
- GNDS_MOUSE
- F6QLL2_XENTR
- PREX2_HUMAN
- R3GEF_HUMAN
- VAV3_HUMAN
- GNOM_ARATH
- F7DDN0_XENTR
- BCAR3_HUMAN
- VAV_HUMAN
- SOS1_MOUSE
- ROGF7_ARATH
- RGL2_HUMAN
- K7N5P2_MOUSE
- SDO1_YEAST
- ARHG2_MOUSE
- RPGFL_HUMAN
- ARGAL_HUMAN
- GAPD1_MOUSE
- RIC8A_MOUSE
- ARH40_MOUSE
- GBF1_HUMAN
- GAPD1_HUMAN
- ABR_MOUSE
- RPGF3_HUMAN
- IQEC1_MOUSE
- GRP1_HUMAN
- Q9W1Q8_DROME
- MTMR5_MOUSE
- DEN4C_HUMAN
- VKIND_HUMAN
- DOCK8_HUMAN
- PROF_SCHPO
- GLR_HUMAN
- SRGEF_MOUSE
- GET3_YEAST
- DOCK3_HUMAN
- SPO13_SCHPO
- TRIO_HUMAN
- EI2BG_HUMAN
- BIG3_MOUSE
- MCF2_HUMAN
- TIAM2_MOUSE
- F7C1K7_XENTR
- ARHG9_HUMAN
- GRP2_MOUSE
- RCC1_HUMAN
- RPGF2_HUMAN
- F6XFM6_XENTR
- RCC1_DROME
- ROGF4_ARATH
- MADD_MOUSE
- ARHGH_HUMAN
- RIC1_MOUSE
- TIAM2_HUMAN
- BCR_MOUSE
- SIF1_DROME
- F6TX02_XENTR
- MADD_HUMAN
- FGD6_HUMAN
- F7BRZ1_XENTR
- DOCK7_HUMAN
- F6WZD6_XENTR
- ANR27_HUMAN
- F7EG59_XENTR
- DSS4_YEAST
- J3QNG1_MOUSE
- ARHGI_MOUSE
- DEN6A_HUMAN
- ARHG7_MOUSE
- MON2_YEAST
- ARHGB_HUMAN
- RGRF1_HUMAN
- ROGFD_ARATH
- DOCK1_HUMAN
- ACM3_MOUSE
- MYCPP_HUMAN
- YL016_YEAST
- ARGAL_MOUSE
- F7B387_XENTR
- TB10A_HUMAN
- MTMR5_HUMAN
- ARHG7_HUMAN
- F7DQQ6_XENTR
- EI2BB_MOUSE
- C3G_DROME
- FGD6_MOUSE
- RPGF2_MOUSE
- SPO14_SCHPO
- ARHGG_HUMAN
- Q9FFV8_ARATH
- DEN5A_HUMAN
- CYH1_HUMAN
- ROGF2_ARATH
- A1ZAU6_DROME
- SOS2_MOUSE
- GRP4_HUMAN
- ECT2_MOUSE
- VAV3_MOUSE
- F6QGX1_XENTR
- F6USI5_XENTR
- DOCK6_MOUSE
- MSS4_MOUSE
- ARH38_HUMAN
- Q9VMF3_DROME
- Q9VPI9_DROME
- F7B2Z4_XENTR
- RPGRH_CAEEL
- ARHGA_MOUSE
- SPRI_DROME
- ARHG5_HUMAN
- F7BK57_XENTR
- BCR_HUMAN
- MCF2L_MOUSE
- B2RW27_MOUSE
- GEF2_SCHPO
- ROGF8_ARATH
- MUK1_YEAST
- Q9VCH4_DROME
- ABR_XENTR
- RIC8B_HUMAN
- L7N464_MOUSE
- BIG3_HUMAN
- TUS1_YEAST
- EI2BE_YEAST
- F6UV14_XENTR
- RIC8A_HUMAN
- ROGFA_ARATH
- ARH38_MOUSE
- DOCK2_HUMAN
- PLCE1_MOUSE
- DOCK7_MOUSE
- Q8SAB7_ARATH
- RIC8B_MOUSE
- VPS9_YEAST
- DEN6B_HUMAN
- BIG1_HUMAN
- DOCK6_HUMAN
- SCD1_SCHPO
- RPGF4_MOUSE
- F7E9P4_XENTR
- TA2R_HUMAN
- DOCK4_MOUSE
- Q7YWN1_CAEEL
- Q80ZR8_MOUSE
- RPGF1_HUMAN
- GEA1_YEAST
- ROGF9_ARATH
- PKHG1_HUMAN
- F7CDK1_XENTR
- RCC1_YEAST
- SH2D3_HUMAN
- BUD5_YEAST
- MSS4_DROME
- DEND3_HUMAN
- FGD4_MOUSE
- ARHG1_HUMAN
- ARG33_HUMAN
- LTE1_YEAST
- ARG28_MOUSE
- ROFG6_ARATH
- SRGEF_HUMAN
- ROGFB_ARATH
- TIAM1_MOUSE
- Q9W541_DROME
- BIG2_HUMAN
- E9PCH4_HUMAN
- G5EEN3_CAEEL
- ITSN1_HUMAN
- DEN1A_HUMAN
- DOC11_HUMAN
- Q68FM7_MOUSE
- Q8IQ97_DROME
- PREX1_HUMAN
- MADD_CAEEL
- PSD1_HUMAN
- LTOR5_MOUSE
- SOS2_HUMAN
- VAV_DROME
- VAV_CAEEL
- F7EBQ3_XENTR
- Q20487_CAEEL
- RGL2_MOUSE
- Q7K4E0_DROME
- GRP4_MOUSE
- EI2BA_MOUSE
- ROGFC_ARATH
- F7CLC8_XENTR
- ITSN1_MOUSE
- ARH37_MOUSE
- RGL1_HUMAN
- G5EBE8_CAEEL
- PI2R_HUMAN
- RCC1_MOUSE
- EF1B_YEAST
- DOCK8_MOUSE
- ARHG4_HUMAN
- RGF2_SCHPO
- F7E820_XENTR
- BIG2_MOUSE
- RGRF2_HUMAN
- DOCK5_HUMAN
- RGRF1_MOUSE
- RIC8A_XENTR
- ARHGG_MOUSE
- BEM2_YEAST
- DOC10_HUMAN
- D3Z0W7_MOUSE
- HERC1_HUMAN
- RGPS2_HUMAN
- RIC8_CAEEL
- L7N250_MOUSE
- DEN6B_MOUSE
- ABR_HUMAN
- PSD4_HUMAN
- Q9D991_MOUSE
- IQEC1_HUMAN
- FARP1_HUMAN
- KALRN_MOUSE
- ROGF1_ARATH
- ROGFE_ARATH
- NGEF_HUMAN
- Q9N5D3_CAEEL
- Q0E949_DROME
- VAV2_MOUSE
- ST5_MOUSE
- SEC2_YEAST
- FNIP1_MOUSE
- DEN6A_MOUSE
- RRP44_MOUSE
- ST5_HUMAN
- GNDS_HUMAN
- J3QMS8_MOUSE
- ARH40_HUMAN
- FGD5_MOUSE
- CYH2_HUMAN
- L7N481_MOUSE
- CDC24_YEAST
- KALRN_HUMAN
- ARHGC_MOUSE
- PCP2_MOUSE
- F6XSC8_XENTR
- MADD_DROME
- FARP2_HUMAN
- RIC1_HUMAN
- MF2L2_HUMAN
- AKP13_HUMAN
- TSC11_YEAST
- VAV2_HUMAN
- RIC8_DROME
- ARHG6_HUMAN
- FGD5_HUMAN
- ARHGC_HUMAN
- RGF3_SCHPO
- TIAM1_HUMAN
- SH23A_HUMAN
- DOC11_MOUSE
- SOS_DROME
- F7EIG6_XENTR
- FNIP1_HUMAN
- TAGAP_MOUSE
- ROGF5_ARATH
- Q9VAS8_DROME
- ARHG6_MOUSE
- MSS4_SCHPO
- ARHG2_HUMAN
- GNL1_ARATH
- RGRF2_MOUSE
- TCTP_DROME
- Q7KVD1_DROME
- GEF3_SCHPO
- MSS4_CAEEL
- B0BMJ6_XENTR
- DNMBP_HUMAN
- ANR27_MOUSE
- F7AG79_XENTR
- EI2BA_CAEEL
- DOCK9_HUMAN
- MOG1_MOUSE
- Q9D5E3_MOUSE
- GEF1_SCHPO
- RGF1_SCHPO
- Q3UHC1_MOUSE
- ARH37_HUMAN
- ARHG8_HUMAN
- F6ZEX5_XENTR
- YHX4_SCHPO
- B3DLU2_XENTR
- Q3V0H9_MOUSE
- ARHG1_MOUSE
- RG84C_DROME
- ECT2L_HUMAN
- DOCK5_MOUSE
- F6PVL3_XENTR
- RCC1_CAEEL
- MTMRD_HUMAN
- ROGF3_ARATH
- HERC2_HUMAN
- CDC25_YEAST
- MOG1_HUMAN
- Q9U364_CAEEL
- SYT1_YEAST
- RRP44_HUMAN
- ROM1_YEAST
- RPGF6_HUMAN
- LTOR1_MOUSE
- PKHG4_HUMAN
- ARHGJ_HUMAN
- MCF2L_HUMAN
- DOCK1_MOUSE
- ECT2_HUMAN
- GEA2_YEAST
- VKIND_MOUSE
- DOCK3_MOUSE
- NGEF_MOUSE
- ALS2_HUMAN
- VAV_MOUSE
- MSS4_HUMAN
- DOCK2_MOUSE
- RAB3I_HUMAN
- RGP1_YEAST
- GNL2_ARATH
- F6SP07_XENTR
- TAGAP_HUMAN
- F6THM7_XENTR
- ARG39_HUMAN
- ARHGA_HUMAN
- YL422_YEAST
- SOS1_HUMAN
- FARP2_MOUSE
- Q9VZL5_DROME
- Q5NCJ1_MOUSE
- ARG39_MOUSE
- PLCE1_HUMAN
- DOCK9_MOUSE
- Q9D506_MOUSE
- RIC1_YEAST
- ROM2_YEAST
- RPGR_HUMAN
- Q9D420_MOUSE