beta-catenin destruction complexImported
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others - phosphorylates beta-catenin, targets it for degradation by the proteasome.
Defined bygo
class Information
alternative label
- APC-Axin-1-beta-catenin complex
- Axin-APC-beta-catenin-GSK3B complex
- beta-catenin degradation complex
has_obo_namespace
cellular_component
preferred label
beta-catenin destruction complex