OntologiesccoclassesGO:0030877   
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beta-catenin destruction complexImported
http://purl.obolibrary.org/obo/GO_0030877

A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others - phosphorylates beta-catenin, targets it for degradation by the proteasome.

Defined bygo
Also appears ingexoretorexo
class Information
alternative label
  • APC-Axin-1-beta-catenin complex
  • Axin-APC-beta-catenin-GSK3B complex
  • beta-catenin degradation complex
has_obo_namespace

cellular_component

preferred label

beta-catenin destruction complex

class Relations