2,8-dihydroxyadenine
A member of the class of 6-aminopurines that is adenine bearing two hydroxy substituents at positions 2 and 8. It is a highly insoluble metabolite of adenine that causes radiolucent urolithiasis. It is produced by individuals who suffer from adenine phosphoribosyltransferase (APRT) deficiency, a rare autosomal recessive error of purine metabolism.
Also appears inslm
Exact Synonyms
6-amino-9H-purine-2,8-diol
Related Synonyms
2,8-DHA
6-amino-2,8-dihydroxypurine
6-amino-purine-2,8-diol
class Information
charge
0
formula
C5H5N5O2
has_dbxref
- CAS:30377-37-8
- FooDB:FDB022018
- HMDB:HMDB0000401
- PMID:10481956
- PMID:15025810
- PMID:16713382
- PMID:20098761
- PMID:21553389
- PMID:23113528
- PMID:24359665
- PMID:24940675
- PMID:25307253
- PMID:26278213
- PMID:27447713
- PMID:27770717
- PMID:28466077
- PMID:28566603
- PMID:28717278
- PMID:29657221
- PMID:29861153
- PMID:30355577
- PMID:31378568
- PMID:31880754
- PMID:32086278
- PMID:32260098
- PMID:32399606
- PMID:32859011
- PMID:33273797
- PMID:33678741
- PMID:34044400
- PMID:34341261
- PMID:34610707
- Wikipedia:2,8-Dihydroxyadenine
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12)
inchikey
XFBOJHLYDJZYSP-UHFFFAOYSA-N
in_subset
mass
167.128
monoisotopicmass
167.04432
smiles
NC1=NC(O)=NC2=C1N=C(O)N2
class Relations
Subclass of
Related from
is tautomer of