varespladib
A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects.
Also appears inslm
Exact Synonyms
({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid
Related Synonyms
2-[2-ethyl-3-oxamoyl-1-(phenylmethyl)indol-4-yl]oxyethanoic acid
2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
A-001
LY 315920
LY-315920
LY315920
S 5920
S-5920
varespladib
varespladibum
class Information
charge
0
formula
C21H20N2O5
has_dbxref
- CAS:172732-68-2
- Chemspider:137248
- DrugBank:DB11909
- HMDB:HMDB0259766
- KEGG:D08107
- Patent:CN101838232
- PDBeChem:VRD
- PMID:10027849
- PMID:12626975
- PMID:15467263
- PMID:16096451
- PMID:20809869
- PMID:21446779
- PMID:23071714
- PMID:27571102
- PMID:29439513
- PMID:30447275
- PMID:30453607
- PMID:30518149
- PMID:31748642
- PMID:32093386
- PMID:32442717
- PMID:32485836
- PMID:32512199
- PMID:32560391
- PMID:32889027
- PMID:33359941
- PMID:33865953
- PMID:33922825
- PMID:34143707
- PMID:34562493
- PMID:34744732
- PMID:34774704
- PMID:34929179
- PMID:35095526
- Wikipedia:Varespladib
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
inchikey
BHLXTPHDSZUFHR-UHFFFAOYSA-N
in_subset
mass
380.400
monoisotopicmass
380.13722
smiles
CCC1=C(C(=O)C(N)=O)C2=C(OCC(O)=O)C=CC=C2N1CC1=CC=CC=C1
class Relations
Subclass of