benzatropine
Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
Exact Synonyms
(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
Benzatropine
Related Synonyms
3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane
3alpha-(diphenylmethoxy)tropane
3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
3endo-benzhydryloxytropane
benzatropina
benzatropine
benzatropinum
benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether
Benztropine
tropine benzohydryl ether
class Information
charge
0
formula
C21H25NO
has_alternative_id
has_dbxref
- Beilstein:90688
- CAS:86-13-5
- DrugBank:DB00245
- Drug_Central:333
- KEGG:C06846
- KEGG:D07511
- Patent:US2595405
- Wikipedia:Benzatropine
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+
inchikey
GIJXKZJWITVLHI-PMOLBWCYSA-N
in_subset
mass
307.42930
monoisotopicmass
307.19361
smiles
[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1
class Relations
Subclass of
Related from
has part