fluticasone propionate
A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl substituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity.
Also appears inslm
Exact Synonyms
6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl propanoate
Fluticasone propionate
Related Synonyms
Cutivate
class Information
charge
0
formula
C25H31F3O5S
has_alternative_id
has_dbxref
- CAS:80474-14-2
- DrugBank:DB00588
- Drug_Central:1225
- KEGG:D01708
- Patent:NL8100707
- Patent:US4335121
- Reaxys:6944704
- Wikipedia:Fluticasone_Propionate
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
inchikey
WMWTYOKRWGGJOA-CENSZEJFSA-N
in_subset
mass
500.57185
monoisotopicmass
500.18443
smiles
[H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
class Relations
Subclass of
- 11beta-hydroxy steroid
- propanoate ester
- steroid ester
- fluorinated steroid
- corticosteroid
- thioester
- 3-oxo-Delta(1),Delta(4)-steroid
- has rolerosomeanti-inflammatory drug
- has rolerosomebronchodilator agent
- has rolerosomeadrenergic agent
- has rolerosomeanti-asthmatic drug
- has rolerosomedermatologic drug
- has rolerosomeanti-allergic agent
- has functional parentsomefluticasone
- has parent hydridesomeandrostane