sapropterin dihydrochloride
The dihydrochloride salt of sapropterin. It is used for the diagnosis and treatment of variant forms of phenylketonuria (hyperphenylalaninaemia) associated with tetrahydrobiopterin deficiency. Natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, and nitric oxide synthetase.
Exact Synonyms
(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride
sapropterin dihydrochloride
Related Synonyms
(6R)-tetrahydrobiopterin dihydrochloride
(6R)-tetrahydrobiopterin hydrochloride
sapropterin 2HCl
sapropterin hydrochloride
class Information
charge
0
formula
C9H17Cl2N5O3
has_dbxref
- Beilstein:4613446
- CAS:69056-38-8
- KEGG:D01798
- PMID:20179079
- PMID:20206791
- PMID:20418136
- PMID:20556789
- PMID:20667834
- PMID:20714359
- PMID:20830319
- PMID:21077779
- PMID:21645517
- PMID:21646032
- PMID:21967857
- PMID:22112818
- PMID:22310224
- Reaxys:12490572
has_obo_namespace
chebi_ontology
inchikey
RKSUYBCOVNCALL-NTVURLEBSA-N
inchi
InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
in_subset
mass
314.16900
monoisotopicmass
313.07084
smiles
Cl.Cl.[H][C@@]1(CNc2nc(N)[nH]c(=O)c2N1)[C@@H](O)[C@H](C)O
class Relations
Subclass of