dizocilpine
An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory.
Also appears inslm
Exact Synonyms
(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene
Related Synonyms
(+)-dizocilpine
(+)-MK-801
dizocilpina
dizocilpine
dizocilpinum
MK 801
MK-801
MK801
class Information
charge
0
formula
C16H15N
has_dbxref
- CAS:77086-21-6
- Chemspider:156718
- KEGG:C13737
- LINCS:LSM-5688
- PDBeChem:BMK
- PMID:28232581
- PMID:29489358
- PMID:29670280
- PMID:30772438
- PMID:31177060
- PMID:32105720
- PMID:32219769
- PMID:32289529
- PMID:32324160
- PMID:32641944
- PMID:32760846
- PMID:32808583
- PMID:32892308
- PMID:32956214
- PMID:32973585
- PMID:33187817
- PMID:33249825
- PMID:33324181
- PMID:33404734
- PMID:33442771
- PMID:33639267
- PMID:33656787
- PMID:33723767
- PMID:33809889
- PMID:33882624
- PMID:33891976
- PMID:33945878
- PMID:33974921
- PMID:34054433
- PMID:34098454
- PMID:34119597
- PMID:34177484
- Wikipedia:Dizocilpine
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C16H15N/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16/h2-9,15,17H,10H2,1H3/t15-,16+/m1/s1
inchikey
LBOJYSIDWZQNJS-CVEARBPZSA-N
in_subset
mass
221.303
monoisotopicmass
221.12045
smiles
[H][C@]12CC3=C(C=CC=C3)[C@](C)(N1)C1=C2C=CC=C1
class Relations
Subclass of
Related from
is conjugate acid of