OntologieschebiclassesCHEBI:4046   
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cyproheptadine
http://purl.obolibrary.org/obo/CHEBI_4046

The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Exact Synonyms
4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
cyproheptadine
CYPROHEPTADINE
Cyproheptadine
Related Synonyms
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
ciproheptadina
cyproheptadine
cyproheptadinum
class Information
charge

0

formula

C21H21N

has_alternative_id
has_obo_namespace

chebi_ontology

inchi

InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3

inchikey

JJCFRYNCJDLXIK-UHFFFAOYSA-N

in_subset

3_STAR

mass

287.39810

monoisotopicmass

287.16740

smiles

CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12

class Relations