(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol
A carbotetracyclic compound that is 5,6,11,12-tetrahydrochrysene substituted by hydroxy groups at positions 2 and 8 and by ethyl groups at positions 5 and 11 (the 5R,11R-stereoisomer). It is an agonist of ER-alpha and antagonist of ER-beta receptors.
Also appears inslm
Exact Synonyms
(5R,11R)-5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
Related Synonyms
(R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
(R,R)-cis-diethyl tetrahydro-2,8-chrysenediol
(R,R)-cis-diethyltetrahydro-2,8-chrysenediol
(R,R)-THC
R,R-THC
class Information
charge
0
formula
C22H24O2
has_dbxref
- CAS:221368-54-3
- Chemspider:394097
- PDBeChem:ETC
- PMID:11953755
- PMID:15582497
- PMID:18719660
- PMID:19505948
- PMID:20097735
- PMID:21940647
- PMID:22099601
- PMID:23688559
- PMID:23857051
- PMID:24134630
- PMID:25167991
- PMID:26855429
- Wikipedia:(R,R)-Tetrahydrochrysene
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C22H24O2/c1-3-13-9-15-11-17(23)6-8-20(15)22-14(4-2)10-16-12-18(24)5-7-19(16)21(13)22/h5-8,11-14,23-24H,3-4,9-10H2,1-2H3/t13-,14-/m1/s1
inchikey
MASYAWHPJCQLSW-ZIAGYGMSSA-N
in_subset
mass
320.432
monoisotopicmass
320.17763
smiles
CC[C@@H]1CC2=C(C=CC(O)=C2)C2=C1C1=C(C[C@H]2CC)C=C(O)C=C1