delavirdine mesylate
The monomethanesulfonic acid salt of delavirdine, a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection.
Also appears inslm
Exact Synonyms
DELAVIRDINE MESYLATE
Delavirdine mesylate
N-[2-({4-[3-(propan-2-ylamino)pyridin-2-yl]piperazin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide methanesulfonate
Related Synonyms
1-(3-(isopropylamino)-2-pyridyl)-4-((5-methanesulfonamidoindol-2-yl)carbonyl)piperazine monomethanesulfonate
Delavirdine mesilate
delavirdine mesilate
delavirdine methanesulfonate
delavirdine monomethanesulfonate
N-{2-[4-(3-Isopropylamino-pyridin-2-yl)-piperazine-1-carbonyl]-1H-indol-5-yl}-methanesulfonamide; compound with methanesulfonic acid
class Information
charge
0
formula
C23H32N6O6S2
has_alternative_id
has_dbxref
- Beilstein:7617470
- CAS:147221-93-0
- KEGG:C08087
- KEGG:D00895
has_obo_namespace
chebi_ontology
inchikey
MEPNHSOMXMALDZ-UHFFFAOYSA-N
inchi
InChI=1S/C22H28N6O3S.CH4O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3,30)31)6-7-18(16)25-20;1-5(2,3)4/h4-8,13-15,24-26H,9-12H2,1-3H3;1H3,(H,2,3,4)
in_subset
mass
552.66700
monoisotopicmass
552.18248
smiles
CS(O)(=O)=O.CC(C)Nc1cccnc1N1CCN(CC1)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1