pizotifen malate
A malate salt resulting from the reaction of equimolar amounts of pizotifen and malic acid. A sedating antihistamine with strong serotonin antagonist and weak antimuscarinic activity, it is used for the treatment of migraine and the prevention of headache attacks during cluster periods.
Also appears inslm
Exact Synonyms
4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxybutanedioate
Related Synonyms
Pizotifen hydrogen malate
Pizotyline malate
Sandomigran
class Information
charge
0
formula
C23H27NO5S
has_dbxref
- CAS:5189-11-7
- KEGG:D08397
- PMID:20884459
- PMID:22002332
- Reaxys:6763530
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18;5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3;2,5H,1H2,(H,6,7)(H,8,9)
inchikey
IWAWCPZVTXCFKD-UHFFFAOYSA-N
in_subset
mass
429.52900
monoisotopicmass
429.16099
smiles
OC(CC(O)=O)C(O)=O.CN1CCC(CC1)=C1c2ccccc2CCc2sccc12