levofloxacin
An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase.
Exact Synonyms
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
Related Synonyms
(-)-Ofloxacin
(-)-ofloxacin
(3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
(S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid
(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(S)-ofloxacin
DR 3355
DR-3355
L-ofloxacin
levofloxacin
levofloxacine
levofloxacino
levofloxacinum
Ofloxacin S-(-)-form
S-(-)-ofloxacin
- chemical entity (200,444)
- molecular entity (196,129)
- main group molecular entity (194,229)
- p-block molecular entity (193,541)
- carbon group molecular entity (189,246)
- organic molecular entity (189,106)
- heteroorganic entity (151,906)
- organic heterocyclic compound (58,446)
- heterocyclic antibiotic (474)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteropolycyclic compound (25,471)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- organochalcogen compound (125,492)
- organooxygen compound (119,501)
- carbon oxoacid (13,739)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbonyl compound (40,169)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbon oxoacid (13,739)
- organooxygen compound (119,501)
- organohalogen compound (4,956)
- organonitrogen compound (70,247)
- organic amino compound (21,666)
- aromatic amine (1,923)
- tertiary amino compound (1,518)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- N-methylpiperazine (87)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- organic amino compound (21,666)
- organic heterocyclic compound (58,446)
- organic acid (14,123)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- organic amino compound (21,666)
- aromatic amine (1,923)
- tertiary amino compound (1,518)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- N-methylpiperazine (87)
- organic molecule (108,434)
- organic cyclic compound (84,676)
- organic aromatic compound (38,947)
- organic heterocyclic compound (58,446)
- heterocyclic antibiotic (474)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteropolycyclic compound (25,471)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- organic polycyclic compound (12,722)
- organic oxo compound (40,189)
- carbonyl compound (40,169)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbonyl compound (40,169)
- organic cyclic compound (84,676)
- heteroorganic entity (151,906)
- organic molecular entity (189,106)
- chalcogen molecular entity (138,750)
- organochalcogen compound (125,492)
- organooxygen compound (119,501)
- carbon oxoacid (13,739)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbonyl compound (40,169)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbon oxoacid (13,739)
- organooxygen compound (119,501)
- oxygen molecular entity (132,386)
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- oxoacid (13,914)
- carbon oxoacid (13,739)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbon oxoacid (13,739)
- oxoacid (13,914)
- organooxygen compound (119,501)
- carbon oxoacid (13,739)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbonyl compound (40,169)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbon oxoacid (13,739)
- hydroxides (27,698)
- organochalcogen compound (125,492)
- halogen molecular entity (5,852)
- fluorine molecular entity (1,782)
- halide (5,680)
- pnictogen molecular entity (88,874)
- nitrogen molecular entity (79,787)
- organonitrogen compound (70,247)
- organic amino compound (21,666)
- aromatic amine (1,923)
- tertiary amino compound (1,518)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- N-methylpiperazine (87)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- organic amino compound (21,666)
- organonitrogen compound (70,247)
- nitrogen molecular entity (79,787)
- carbon group molecular entity (189,246)
- s-block molecular entity (30,789)
- hydrogen molecular entity (30,008)
- hydroxides (27,698)
- oxoacid (13,914)
- carbon oxoacid (13,739)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbon oxoacid (13,739)
- oxoacid (13,914)
- hydroxides (27,698)
- hydrogen molecular entity (30,008)
- p-block molecular entity (193,541)
- polyatomic entity (140,025)
- heteroatomic molecular entity (60,413)
- halide (5,680)
- hydroxides (27,698)
- oxoacid (13,914)
- carbon oxoacid (13,739)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbon oxoacid (13,739)
- oxoacid (13,914)
- molecule (108,973)
- cyclic compound (85,378)
- aromatic compound (38,998)
- heterocyclic compound (58,598)
- heteromonocyclic compound (13,704)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteromonocyclic compound (13,701)
- heteropolycyclic compound (25,474)
- heterotricyclic compound (5,216)
- organic heteropolycyclic compound (25,471)
- organic heterocyclic compound (58,446)
- heterocyclic antibiotic (474)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteropolycyclic compound (25,471)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
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- monocyclic compound (13,709)
- heteromonocyclic compound (13,704)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteromonocyclic compound (13,701)
- heteromonocyclic compound (13,704)
- organic cyclic compound (84,676)
- organic aromatic compound (38,947)
- organic heterocyclic compound (58,446)
- heterocyclic antibiotic (474)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteropolycyclic compound (25,471)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- organic polycyclic compound (12,722)
- polycyclic compound (35,878)
- heteropolycyclic compound (25,474)
- heterotricyclic compound (5,216)
- organic heteropolycyclic compound (25,471)
- organic polycyclic compound (12,722)
- heteropolycyclic compound (25,474)
- organic molecule (108,434)
- organic cyclic compound (84,676)
- organic aromatic compound (38,947)
- organic heterocyclic compound (58,446)
- heterocyclic antibiotic (474)
- organic heteromonocyclic compound (13,701)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- piperazines (1,058)
- organic heteropolycyclic compound (25,471)
- organonitrogen heterocyclic compound (35,353)
- organonitrogen heterocyclic antibiotic (408)
- piperazines (1,058)
- N-alkylpiperazine (222)
- N-arylpiperazine (239)
- organic polycyclic compound (12,722)
- organic oxo compound (40,189)
- carbonyl compound (40,169)
- carboxylic acid (13,728)
- monocarboxylic acid (7,344)
- oxo carboxylic acid (675)
- carboxylic acid (13,728)
- carbonyl compound (40,169)
- organic cyclic compound (84,676)
- cyclic compound (85,378)
- heteroatomic molecular entity (60,413)
- main group molecular entity (194,229)
- molecular entity (196,129)
class Information
charge
0
formula
C18H20FN3O4
has_alternative_id
has_dbxref
- CAS:100986-85-4
- DrugBank:DB01137
- Drug_Central:1569
- HMDB:HMDB0001929
- KEGG:C07660
- KEGG:D08120
- LINCS:LSM-5270
- PDBeChem:LFX
- PMID:10803495
- PMID:11141388
- PMID:11181130
- PMID:11249554
- PMID:11558453
- PMID:11898264
- PMID:11975700
- PMID:14581720
- PMID:15969945
- PMID:17549677
- PMID:19212411
- PMID:20596531
- PMID:2079448
- PMID:21075586
- PMID:21965436
- PMID:21974858
- PMID:22088660
- PMID:22221614
- PMID:23965305
- PMID:26792525
- PMID:27050128
- PMID:34323366
- PMID:34824229
- PMID:36076992
- PMID:36102678
- PMID:36119964
- PMID:36135690
- PMID:36314364
- PMID:36328279
- PMID:8656585
- PMID:8957581
- PMID:9068926
- PMID:9624783
- Reaxys:5385660
- VSDB:1899
- Wikipedia:Levofloxacin
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
inchikey
GSDSWSVVBLHKDQ-JTQLQIEISA-N
in_subset
mass
361.373
monoisotopicmass
361.14378
smiles
C[C@H]1COC2=C(N3CCN(C)CC3)C(F)=CC3=C2N1C=C(C(O)=O)C3=O
class Relations
Subclass of
- 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- quinolone antibiotic
- fluoroquinolone antibiotic
- has rolerosomeantibacterial drug
- has rolerosomeEC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
- has rolerosometopoisomerase IV inhibitor
- has rolerosomeDNA synthesis inhibitor
- is conjugate acid ofsomelevofloxacin(1-)
- is enantiomer ofsomedextrofloxacin