OntologieschebiclassesCHEBI:64187   
JSON document
benserazide
http://purl.obolibrary.org/obo/CHEBI_64187

A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Also appears infideoprideslmefodron
Exact Synonyms
2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide
Related Synonyms
benserazida
benserazide
benserazidum
DL-serine 2-(2,3,4-trihydroxybenzyl)hydrazide
DL-serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
Ro 4-4602
Ro 44602
class Information
charge

0

formula

C10H15N3O5

has_obo_namespace

chebi_ontology

inchi

InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)

inchikey

BNQDCRGUHNALGH-UHFFFAOYSA-N

in_subset

3_STAR

mass

257.24320

monoisotopicmass

257.10117

smiles

NC(CO)C(=O)NNCc1ccc(O)c(O)c1O

class Relations