naproxen
A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes.
Exact Synonyms
(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
naproxen
Naproxen
Related Synonyms
(+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(+)-(S)-Naproxen
(+)-2-(6-Methoxy-2-naphthyl)propionic acid
(+)-2-(Methoxy-2-naphthyl)-propionic acid
(+)-2-(Methoxy-2-naphthyl)-propionsaeure
(+)-Naproxen
(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-(+)-Naproxen
(S)-2-(6-Methoxy-2-naphthyl)propanoic acid
(S)-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-Naproxen
naproxen
naproxene
naproxeno
naproxenum
class Information
charge
0
formula
C14H14O3
has_alternative_id
has_dbxref
- Beilstein:3591067
- CAS:22204-53-1
- DrugBank:DB00788
- Drug_Central:1883
- HMDB:HMDB0001923
- KEGG:D00118
- LINCS:LSM-5689
- Patent:US3904682
- Patent:US4009197
- PMID:18044350
- PMID:24478225
- PMID:9784154
- Wikipedia:Naproxen
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
inchikey
CMWTZPSULFXXJA-VIFPVBQESA-N
in_subset
mass
230.25920
monoisotopicmass
230.09429
smiles
COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
class Relations
Subclass of
- monocarboxylic acid
- methoxynaphthalene
- has rolerosomenon-steroidal anti-inflammatory drug
- has rolerosomenon-narcotic analgesic
- has rolerosomeantipyretic
- has rolerosomexenobiotic
- has rolerosomegout suppressant
- has rolerosomecyclooxygenase 2 inhibitor
- has rolerosomecyclooxygenase 1 inhibitor
- has rolerosomeenvironmental contaminant
- has rolerosomedrug allergen
- is conjugate acid ofsomenaproxen(1-)
Related from
has functional parent
is conjugate base of