ofloxacin
A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Exact Synonyms
rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
Related Synonyms
(+-)-ofloxacin
(3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
DL 8280
DL-8280
Exocin
Floxin
Gailuoxian
HOE 280
HOE-280
Ocuflox
ofloxacin
ofloxacine
ofloxacino
ofloxacinum
OFLX
ORF 18489
Oxaldin
Prifloxcin
Prifloxin
rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
rac-ofloxacin
racemic ofloxacin
Tarivid
Visiren
class Information
charge
0
formula
C18H20FN3O4
has_alternative_id
has_dbxref
- CAS:82419-36-1
- DrugBank:DB01165
- Drug_Central:1981
- HMDB:HMDB0015296
- KEGG:C07321
- KEGG:D00453
- LINCS:LSM-4370
- MetaCyc:CPD-12843
- PMID:11710934
- PMID:11903499
- PMID:12827054
- PMID:15008519
- PMID:15557076
- PMID:16669862
- PMID:1804789
- PMID:19646516
- PMID:24497308
- PMID:24550337
- PMID:3469159
- PMID:3546152
- PMID:35897550
- PMID:36004580
- PMID:36228398
- PMID:36268299
- PMID:6960805
- PMID:7884650
- PMID:9228220
- Reaxys:3657947
- VSDB:1898
- Wikipedia:Ofloxacin
has_obo_namespace
chebi_ontology
in_subset
mass
361.373
monoisotopicmass
361.14378
class Relations
Subclass of
- racemate
- quinolone antibiotic
- fluoroquinolone antibiotic
- has partbfosomedextrofloxacin
- has partbfosomelevofloxacin
- has rolerosomeantiinfective agent
- has rolerosomeantibacterial drug
- has rolerosomeEC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
- has rolerosometopoisomerase IV inhibitor
- has rolerosomeDNA synthesis inhibitor