A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission.
class Information
0
C63H98N18O13S
- CAS:33507-63-0
- FooDB:FDB002259
- HMDB:HMDB0001897
- KEGG:C16094
- Patent:US2010190722
- PMID:16729222
- PMID:28474564
- PMID:30935032
- PMID:32634530
- PMID:33688239
- PMID:34017371
- PMID:34915568
- PMID:35054936
- PMID:35269726
- PMID:35402619
- PMID:35485451
- PMID:35507035
- PMID:35525773
- PMID:35779793
- PMID:35806893
- PMID:35820276
- PMID:35856812
- PMID:35884599
- PMID:35904495
- PMID:35948329
- PMID:35955767
- PMID:36001730
- PMID:36040535
- PMID:36067981
- PMID:36146768
- PMID:36165925
- PMID:36197354
- PMID:36351068
- PMID:36361972
- PMID:36385363
- PMID:36414415
- PMID:6196797
- PMID:7541689
- Wikipedia:Substance_P
chebi_ontology
InChI=1S/C63H98N18O13S/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(88)42(23-25-50(66)82)75-55(87)43(24-26-51(67)83)76-59(91)49-22-14-31-81(49)62(94)44(20-10-11-28-64)77-60(92)48-21-13-30-80(48)61(93)40(65)19-12-29-71-63(69)70/h4-9,15-18,37,40-49H,10-14,19-36,64-65H2,1-3H3,(H2,66,82)(H2,67,83)(H2,68,85)(H,72,86)(H,73,84)(H,74,89)(H,75,87)(H,76,91)(H,77,92)(H,78,90)(H,79,88)(H4,69,70,71)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-/m0/s1
ADNPLDHMAVUMIW-CUZNLEPHSA-N
1347.650
1346.72815
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(N)=N)C(N)=O