prednisone
A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Exact Synonyms
17,21-dihydroxypregna-1,4-diene-3,11,20-trione
Related Synonyms
1,2-Dehydrocortisone
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
Dehydrocortisone
prednison
prednisona
prednisone
prednisonum
class Information
charge
0
formula
C21H26O5
has_dbxref
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
inchikey
XOFYZVNMUHMLCC-ZPOLXVRWSA-N
in_subset
mass
358.42810
monoisotopicmass
358.17802
smiles
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
class Relations
Subclass of
- primary alpha-hydroxy ketone
- tertiary alpha-hydroxy ketone
- glucocorticoid
- 17alpha-hydroxy steroid
- 21-hydroxy steroid
- 20-oxo steroid
- 11-oxo steroid
- C21-steroid
- 3-oxo-Delta(1),Delta(4)-steroid
- has rolerosomeanti-inflammatory drug
- has rolerosomeantineoplastic agent
- has rolerosomeimmunosuppressive agent
- has rolerosomeadrenergic agent
- has rolerosomeprodrug
Related from