3-iodothyronamine
An organoiodine compound that is benzene substituted by 4-hydroxyphenoxy, iodo, and 2-aminoethyl groups at positions 1, 2, and 4, respectively. It is a thyroid hormone metabolite and a potent agonist of trace amine-associated receptor 1.
Also appears inslm
Exact Synonyms
4-[4-(2-aminoethyl)-2-iodophenoxy]phenol
Related Synonyms
3-T1AM
4-[4-(2-azanylethyl)-2-iodanyl-phenoxy]phenol
T1AM
class Information
charge
0
formula
C14H14INO2
has_dbxref
- CAS:712349-95-6
- FooDB:FDB111734
- HMDB:HMDB0060524
- PDBeChem:UJF
- PMID:15146179
- PMID:21490071
- PMID:25878061
- PMID:27676423
- PMID:27815171
- PMID:28368510
- PMID:28711308
- PMID:29311919
- PMID:29593543
- PMID:29786646
- PMID:30383216
- PMID:30524369
- PMID:30610043
- PMID:31075293
- PMID:31434215
- PMID:31698479
- PMID:31709926
- PMID:32110992
- PMID:32114521
- PMID:32162616
- PMID:32183490
- PMID:32257954
- PMID:32375297
- PMID:32450582
- PMID:32685439
- PMID:33077693
- PMID:33799468
- PMID:33981284
- PMID:34717926
- PMID:35265713
- PMID:35269859
- PMID:35280406
- PMID:35736409
- PMID:35882940
- PMID:36143389
- PMID:37245501
- PMID:37381696
- PMID:37511328
- PMID:37762153
- PMID:37779034
- PMID:37822560
- PMID:37842308
- PMID:37935376
- PMID:38750597
- Wikipedia:3-Iodothyronamine
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C14H14INO2/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12/h1-6,9,17H,7-8,16H2
inchikey
XIINYOJWNGOUPF-UHFFFAOYSA-N
in_subset
mass
355.175
monoisotopicmass
355.00692
smiles
NCCC1=CC(I)=C(OC2=CC=C(O)C=C2)C=C1
class Relations
Subclass of
- phenols
- aromatic ether
- organoiodine compound
- primary amino compound
- has rolerosometrace amine-associated receptor 1 agonist
- has rolerosomeneuroprotective agent
- has rolerosomeanti-inflammatory agent
- has rolerosomeapoptosis inhibitor
- has rolerosomeanti-obesity agent
- has rolerosomecardioprotective agent
- has rolerosomehuman blood serum metabolite
- is conjugate base ofsome3-iodothyronamine(1+)
Related from
is conjugate acid of