Ontologiesβ–Έcidoβ–Έclassesβ–ΈCHEBI:75991   
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trametinib dimethyl sulfoxideImported
http://purl.obolibrary.org/obo/CHEBI_75991

An addition compound obtained by combining equimolar amounts of trametinib and dimethyl sulfoxide. Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment.

Defined bychebi
Also appears inslm
Exact Synonyms
N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide--(methylsulfinyl)methane (1/1)
Related Synonyms
GSK1120212
GSK1120212B
JTP 74057
Mekinist
Trametinib DMSO
class Information
charge

0

definition source
formula
  • C26H23FIN5O4.C2H6OS
  • C28H29FIN5O5S
has_obo_namespace

chebi_ontology

inchi

InChI=1S/C26H23FIN5O4.C2H6OS/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34;1-4(2)3/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34);1-2H3

inchikey

OQUFJVRYDFIQBW-UHFFFAOYSA-N

mass

693.52800

monoisotopicmass

693.09181

smiles

CS(C)=O.CC(=O)Nc1cccc(c1)-n1c2c(C)c(=O)n(C)c(Nc3ccc(I)cc3F)c2c(=O)n(C2CC2)c1=O

class Relations