rosuvastatinImported
A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer).
Defined bychebi
Exact Synonyms
(3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
Related Synonyms
(3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
rosuvastatin
class Information
charge
0
formula
C22H28FN3O6S
has_dbxref
- CAS:287714-41-4
- DrugBank:DB01098
- Drug_Central:2406
- HMDB:HMDB0015230
- KEGG:D08492
- Patent:US2013035316
- PMID:17970755
- PMID:18509206
- PMID:19724024
- PMID:19956889
- PMID:23806820
- PMID:23881596
- PMID:23944632
- PMID:24072337
- PMID:24076297
- PMID:24076283
- PMID:24156555
- PMID:24163149
- PMID:24230979
- PMID:24253250
- PMID:24259612
- PMID:24304551
- PMID:24333476
- PMID:24353409
- PMID:24410968
- PMID:24417785
- PMID:24434545
- PMID:24440960
- PMID:24440231
- PMID:24444439
- PMID:24452083
- PMID:24456217
- PMID:24467235
- Reaxys:9670765
- Wikipedia:Rosuvastatin
has_obo_namespace
chebi_ontology
has_RxCUI
301542
inchi
InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
inchikey
BPRHUIZQVSMCRT-VEUZHWNKSA-N
in_subset
mass
481.53800
monoisotopicmass
481.16828
smiles
CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O
class Relations
Subclass of
- sulfonamidechebi
- dihydroxy monocarboxylic acidchebi
- pyrimidineschebi
- monofluorobenzeneschebi
- statin (synthetic)chebi
- has rolerosomexenobioticchebi
- has rolerosomeCETP inhibitorchebi
- has rolerosomeanti-inflammatory agentchebi
- has rolerosomecardioprotective agentchebi
- has rolerosomeenvironmental contaminantchebi
- has functional parentsomehept-6-enoic acidchebi
- is conjugate acid ofsomerosuvastatin(1-)chebi
Related from
is conjugate base of