linezolidImported
An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex.
Defined bychebi
Exact Synonyms
Linezolid
N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Related Synonyms
linezolid
N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
class Information
charge
0
formula
C16H20FN3O4
has_alternative_id
has_dbxref
- CAS:165800-03-3
- DrugBank:DB00601
- Drug_Central:1584
- KEGG:C08146
- KEGG:D00947
- LINCS:LSM-5750
- Patent:US5688792
- Patent:WO957271
- PDBeChem:ZLD
- PMID:21740298
- PMID:21815204
- PMID:21899392
- PMID:22037854
- PMID:22064533
- PMID:22064542
- PMID:22110086
- PMID:22134348
- PMID:22139199
- PMID:22214776
- PMID:22230331
- PMID:22247123
- Reaxys:7496939
- Wikipedia:Linezolid
has_obo_namespace
chebi_ontology
has_RxCUI
190376
inchi
InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
inchikey
TYZROVQLWOKYKF-ZDUSSCGKSA-N
in_subset
mass
337.34610
monoisotopicmass
337.14378
smiles
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCOCC2)c(F)c1