loperamideImported
A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Defined bychebi
Exact Synonyms
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
loperamide
Loperamide
Related Synonyms
loperamida
loperamide
loperamidum
class Information
charge
0
formula
C29H33ClN2O2
has_dbxref
- CAS:53179-11-6
- DrugBank:DB00836
- Drug_Central:1599
- HMDB:HMDB0004999
- KEGG:C07080
- KEGG:D08144
- LINCS:LSM-3365
- Patent:FR2100711
- Patent:US3714159
- PMID:15900907
- PMID:19034106
- PMID:24398461
- Reaxys:1558273
- Wikipedia:Loperamide
has_obo_namespace
chebi_ontology
has_RxCUI
6468
inchi
InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3
inchikey
RDOIQAHITMMDAJ-UHFFFAOYSA-N
in_subset
mass
477.03800
monoisotopicmass
476.22306
smiles
CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1
class Relations
Subclass of
- piperidineschebi
- tertiary alcoholchebi
- monocarboxylic acid amidechebi
- monochlorobenzeneschebi
- is_bearer_ofsomefunction-activating mu receptor binding disposition
- has rolerosomeanticoronaviral agentchebi
- has rolerosomemu-opioid receptor agonistchebi
- has rolerosomeantidiarrhoeal drugchebi
- is conjugate base ofsomeloperamide(1+)chebi
Related from
is conjugate acid of