A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses
class Information
0
C21H30O5
- Beilstein:1354819
- CAS:50-23-7
- DrugBank:DB00741
- Drug_Central:1388
- KEGG:C00735
- KEGG:D00088
- LINCS:LSM-5980
- LIPID_MAPS_instance:LMST02030001
- Patent:US2602769
- PDBeChem:HCY
- PMID:10438974
- PMID:2268561
- Wikipedia:Hydrocortisone
chebi_ontology
InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
JYGXADMDTFJGBT-VWUMJDOOSA-N
362.45990
362.20932
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
class Relations
- 17alpha-hydroxy-C21-steroidchebi
- primary alpha-hydroxy ketonechebi
- tertiary alpha-hydroxy ketonechebi
- glucocorticoidchebi
- 21-hydroxy steroidchebi
- 11beta-hydroxy steroidchebi
- 20-oxo steroidchebi
- 3-oxo-Delta(4) steroidchebi
- has rolerosomeanti-inflammatory drugchebi
- has rolerosomeanti-asthmatic drugchebi
- has rolerosomeanti-allergic agentchebi
- has rolerosomemouse metabolitechebi
- has rolerosomehuman metabolitechebi
- has rolerosomedrug allergenchebi
- has parent hydridesomepregnanechebi