pyridoxamineImported
A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy.
Defined bychebi
Exact Synonyms
4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
Pyridoxamine
Related Synonyms
4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL
PM
class Information
charge
0
formula
C8H12N2O2
has_alternative_id
has_dbxref
- Beilstein:6993
- CAS:85-87-0
- Chemspider:1023
- FooDB:FDB021819
- Gmelin:774473
- HMDB:HMDB0001431
- KEGG:C00534
- KNApSAcK:C00007504
- MetaCyc:PYRIDOXAMINE
- PDBeChem:PXM
- PMID:1400785
- PMID:15369738
- PMID:18434162
- PMID:19212411
- PMID:23504149
- PMID:23841818
- PMID:24094054
- PMID:2580028
- PMID:33535220
- PMID:33665688
- PMID:7710125
- PMID:8054960
- Reaxys:6993
- Wikipedia:Pyridoxamine
has_obo_namespace
chebi_ontology
inchi
InChI=1S/C8H12N2O2/c1-5-8(12)7(2-9)6(4-11)3-10-5/h3,11-12H,2,4,9H2,1H3
inchikey
NHZMQXZHNVQTQA-UHFFFAOYSA-N
in_subset
mass
168.19316
monoisotopicmass
168.08988
smiles
Cc1ncc(CO)c(CN)c1O
class Relations
Subclass of
- vitamin B6chebi
- monohydroxypyridinechebi
- hydroxymethylpyridinechebi
- aminoalkylpyridinechebi
- has rolerosomeiron chelatorchebi
- has rolerosomemouse metabolitechebi
- has rolerosomeSaccharomyces cerevisiae metabolitechebi
- has rolerosomenephroprotective agentchebi
- has rolerosomeplant metabolitechebi
- has rolerosomeEscherichia coli metabolitechebi
- has rolerosomehuman metabolitechebi
- is conjugate base ofsomepyridoxaminium(1+)chebi
Related from
has functional parent
is conjugate acid of