cytochrome-c oxidase activity
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
Exact Synonyms
cytochrome c oxidase activity
Related Synonyms
complex IV (mitochondrial electron transport) activity
cytochrome oxidase activity
Warburg's respiratory enzyme activity
Narrow Synonyms
aa3-type cytochrome c oxidase
ba3-type cytochrome c oxidase
caa3-type cytochrome c oxidase
cbb3-type cytochrome c oxidase
cytochrome a3 activity
cytochrome aa3 activity
indophenol oxidase
indophenolase
class Information
has_dbxref
- EC:7.1.1.9
- MetaCyc:CYTOCHROME-C-OXIDASE-RXN
- Reactome:R-HSA-163214
- RHEA:11436
has_obo_namespace
molecular_function
class Relations
Subclass of
- electron transfer activity
- proton transmembrane transporter activity
- oxidoreduction-driven active transmembrane transporter activity
- oxidoreductase activity, acting on a heme group of donors
- active monoatomic ion transmembrane transporter activity
- has participantrosomewaterchebi
- has participantrosomehydronchebi
- has participantrosomedioxygenchebi
- has participantrosomeiron(2+)chebi
- has participantrosomeiron(3+)chebi
Related from
capable of
positively regulates