OntologiesgoclassesGO:0004467   
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long-chain fatty acid-CoA ligase activity
http://purl.obolibrary.org/obo/GO_0004467

Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see short-chain fatty acidchebi, medium-chain fatty acidchebi, long-chain fatty acidchebi and very long-chain fatty acidchebi). Note that this term has a MetaCyc pathway reference as the pathway only has a single step.

Also appears infypogexoccoretorexo + 1
Exact Synonyms
long-chain acyl-CoA synthetase activity
long-chain-fatty-acid-CoA ligase activity
long-chain-fatty-acyl-CoA synthetase activity
Related Synonyms
acyl-CoA ligase activity
acyl-CoA synthetase activity
fatty acid thiokinase (long-chain) activity
LCFA synthetase activity
lignoceroyl-CoA synthase activity
long chain fatty acyl-CoA synthetase activity
long-chain acyl CoA synthetase activity
long-chain acyl-coenzyme A synthetase activity
long-chain fatty acid activation
long-chain fatty acyl coenzyme A synthetase activity
thiokinase
Narrow Synonyms
pristanoyl-CoA synthetase
stearoyl-CoA synthetase
Broad Synonyms
acyl-activating enzyme activity
class Information
has_alternative_id

GO_0003996

has_dbxref
  • EC:6.2.1.3
  • MetaCyc:PWY-5143
  • MetaCyc:RXN-7904
  • Reactome:R-HSA-192137
  • Reactome:R-HSA-193727
  • Reactome:R-HSA-193743
  • Reactome:R-HSA-5696004
  • Reactome:R-HSA-159425
  • Reactome:R-HSA-548843
  • Reactome:R-HSA-193407
  • Reactome:R-HSA-201035
  • Reactome:R-HSA-2046098
  • Reactome:R-HSA-193401
  • Reactome:R-HSA-193766
  • Reactome:R-HSA-9734535
  • Reactome:R-HSA-193711
  • Reactome:R-HSA-193424
  • Reactome:R-HSA-2046085
  • RHEA:15421
has_obo_namespace

molecular_function

class Relations