dopamine beta-monooxygenase activity
Catalysis of the reaction: L-ascorbate + dopamine + O2 = (R)-noradrenaline + dehydroascorbate + H2O.
Exact Synonyms
dopamine b-hydroxylase activity
Related Synonyms
(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity
3,4-dihydroxyphenethylamine beta-oxidase activity
3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)
4-(2-aminoethyl)pyrocatechol beta-oxidase activity
dopa beta-hydroxylase activity
dopamine beta-hydroxylase activity
dopamine beta-oxidase activity
dopamine hydroxylase activity
dopamine-B-hydroxylase activity
MDBH (membrane-associated dopamine beta-monooxygenase)
oxygenase, dopamine beta-mono-
phenylamine beta-hydroxylase activity
SDBH (soluble dopamine beta-monooxygenase)
class Information
has_dbxref
- EC:1.14.17.1
- KEGG_REACTION:R02535
- MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN
- Reactome:R-HSA-209891
- RHEA:19117
has_obo_namespace
molecular_function
class Relations
Subclass of
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
- has participantrosomewaterchebi
- has participantrosomedioxygenchebi
- has participantrosomeL-ascorbatechebi
- has participantrosomemonodehydro-L-ascorbate(1-)chebi
- has participantrosomedopaminium(1+)chebi
- has participantrosome(R)-noradrenaline(1+)chebi