nitric-oxide synthase activity
Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
Exact Synonyms
nitric oxide synthase activity
Related Synonyms
endothelium-derived relaxation factor-forming enzyme activity
endothelium-derived relaxing factor synthase activity
L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity
NADPH-diaphorase activity
nitric oxide synthetase activity
nitric-oxide synthetase activity
NO synthase activity
class Information
has_dbxref
- EC:1.14.13.39
- MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN
- Reactome:R-HSA-418436
- Reactome:R-HSA-202127
- RHEA:19897
has_obo_namespace
molecular_function
class Relations
Subclass of
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
- has participantrosomewaterchebi
- has participantrosomehydronchebi
- has participantrosomedioxygenchebi
- has participantrosomenitric oxidechebi
- has participantrosomeL-argininium(1+)chebi
- has participantrosomeL-citrulline zwitterionchebi
- has participantrosomeNADPH(4-)chebi
- has participantrosomeNADP(3-)chebi
Related from
positively regulates
negatively regulates
directly negatively regulates
capable of
directly regulates